Results 241 to 250 of about 189,815 (388)

Fast Registration Algorithm for Laser Point Cloud Based on 3D-SIFT Features. [PDF]

open access: yesSensors (Basel)
Yang L   +8 more
europepmc   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang   +8 more
wiley   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

open access: yesAdvanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He   +16 more
wiley   +1 more source

Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
Salt stress endangers coastal cereal crops, requiring resilient crop solutions. This study employs machine learning (KANMB) to analyze multi‐omics data from halophyte Spartina alterniflora, revealing 226 salt‐stress biomarkers and linking them to tolerance pathways. The MYB gene SaMYB35 regulates flavonoid biosynthesis under salinity.
Shoukun Chen   +7 more
wiley   +1 more source

Synergistic Machine Learning Guided Discovery of ABa3(BSe3)2X (A = Rb, Cs; X = Cl, Br, I): A Promising Family as Property‐Balanced IR Functional Materials

open access: yesAdvanced Science, EarlyView.
A synergistic framework for interpretable ML‐assisted target discovery of selenoborates is developed. ABa3(BSe3)2X (A = Rb, Cs; X = Cl, Br, I) are successfully predicted and synthesized, exhibiting significant potential to be promising IR functional materials. This work promotes the cooperation of ML technology and materials science.
Yihan Yun   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy