Results 241 to 250 of about 539,599 (306)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Guiding principles for clinical research on substance use disorders in rural communities. [PDF]

J Subst Use Addict Treat
Bunting AM, Winstanley EL.
europepmc   +1 more source

Spatial Transcriptomics and Bulk RNA‐Seq Analysis Revealed Molecular Classification of Invasive Lobular Carcinoma

Cancer Science, EarlyView.
Spatial transcriptomics and bulk RNA‐seq data analysis revealed the molecular characteristics of invasive lobular carcinoma (ILC). ILC was classified into three clusters: proliferative, immunoreactive, and stromal‐rich, with different prognoses. ABSTRACT Invasive lobular carcinoma (ILC) is a special type of breast cancer.
Momoko Tokura, Jun Nakayama, Hironori Suzuki, Mieko Ochi, Miyaka Umemori, Sho Shiino, Masayuki Yoshida, Shin Takayama, Yasushi Yatabe, Yusuke Yamamoto   +9 more
wiley   +1 more source

Spiritual interventions and self-stigma in the family of person who use drugs: a clinical trial study. [PDF]

Sci Rep
Sedieghifar Z, Jalali A, Rahmati M, Ezzati E, Salari N.   +4 more
europepmc   +1 more source

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua, Xinyi Wu, Tahani Al Kindi, Bulent O. Yildiz, Aya Mousa, Loyal Pattuwage, Helena Teede, Anju E. Joham, Chau Thien Tay   +8 more
wiley   +1 more source

Development of an artificial intelligence-based computer-aided detection system for routine gastric biopsy diagnosis. [PDF]

J Pathol Inform
Taniyama D, Kuraoka K, Saito A, Kido A, Shirai A, Yamamoto R, Mano M, Teramoto N, Miura S, Akagi M, Katayama N, Kawasaki T, Nakajima C, Kikuchi S, Taniyama K.   +14 more
europepmc   +1 more source

Comparison of Long vs. Short Concave Neck in One‐Piece Implants Inserted 1 mm Subcrestally: A Pre‐Clinical In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim was to assess the influence of one‐piece implant concave neck height on soft‐ and hard‐tissue healing on a canine model. Material and Methods Monoblock implants with a transgingival concave neck were randomly inserted 1 mm subcrestally.
Hadi Antoun, Frank Bonnet, María Permuy Mendaña, Daniele Botticelli, Giovanna Iezzi, Morena Petrini   +5 more
wiley   +1 more source

Baseline associations between thoracic expansion, respiratory function, and pain in nonspecific low back pain: A cross-sectional analysis from the DIAFRAGMA trial. [PDF]

PLoS One
Vera-Serrano FJ, Vinolo-Gil MJ, Rebollo-Ramos M, Estebanez-Pérez MJ, Pastora-Bernal JM, Díaz-Mancha JA.   +5 more
europepmc   +1 more source

Interventions for children with developmental coordination disorder: A scoping review

Developmental Medicine &Child Neurology, EarlyView.
This scoping review identified 13 differing categories of interventions delivered to children with developmental coordination disorder worldwide ranging from task oriented, motor skills training, and sensorimotor approaches to sports training approaches and health promotion, with motor performance mostly reported as outcome and similar effectiveness ...
Dorothee Jelsma, Zdenek Svoboda, Reza Abdollahipour, Miriam Palomo Nieto, Miguel Villa De Gregorio, Kamila Banatova, Farhad Ghadiri, Fatemeh Alaei, Paola Violasdotter Nilsson, Dido Green   +9 more
wiley   +1 more source

Can one use serum Lactate Concentration to Correct for the Anion gap? [PDF]

J Intensive Care Med
Sam R, Zhou N, Fernandez E, Amatruda J, Tzamaloukas AH.   +4 more
europepmc   +1 more source