Results 51 to 60 of about 2,359,573 (306)

Stochastic sigma-convergence and applications

open access: yes, 2011
Motivated by the fact that in nature almost all phenomena behave randomly in some scales and deterministically in some other scales, we build up a framework suitable to tackle both deterministic and stochastic homogenization problems simultaneously, and also separately.
Sango, Mamadou, Woukeng, Jean Louis
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Stability analysis for a recurrent sigma‒pi‒sigma neural network based on a batch gradient algorithm with L2 regularization [PDF]

open access: yesPeerJ Computer Science
Higher-order neural networks (HONNs) have more powerful nonlinear mapping capabilities than traditional feed-forward neural networks do. The recurrent sigma-pi-sigma neural network (RSPSNN), a multilayer higher-order neural network, suffers from slow ...
Liqing Zhang   +4 more
doaj   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

CONVERGENCE OF HEALTH EXPENDITURE IN EU 12 AND V4 STATES

open access: yesCopernican Journal of Finance & Accounting, 2017
The subject of this paper is an attempt to assess the level of convergence of government health spending in the European Union countries. The ever-increasing level of life expectancy, demographic changes, including the aging of society in many European ...
Piotr Kułyk, Łukasz Augustowski
doaj   +3 more sources

Global Health Policy Position Statement [PDF]

open access: yes, 2018
Issue being addressed: Clarification of Sigma Theta Tau International Honor Society\u27s desired role in health ...
Sigma Theta Tau International
core   +1 more source

Corporate tax rates in the EU: harmonisation and competition from the perspective of convergence analyses

open access: yesEntrepreneurship and Sustainability Issues
Tax policy plays a key role in shaping the economic environment and the competitiveness of states within the common European market. Given the deepening economic integration within the EU, analysing tax system convergence is becoming increasingly ...
Šimon Uličný, Alena Andrejovská
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Homogenization of a 2D Tidal Dynamics Equation

open access: yesMathematics, 2020
This work deals with the homogenization of two dimensions’ tidal equations. We study the asymptotic behavior of the sequence of the solutions using the sigma-convergence method.
Giuseppe Cardone   +2 more
doaj   +1 more source

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