Results 91 to 100 of about 7,711,295 (297)
Twists of trigonometric sigma models
We introduce the ℤ N -twisted trigonometric sigma models, a new class of integrable deformations of the principal chiral model. Starting from 4d Chern-Simons theory on a cylinder, the models are constructed by introducing a ℤ N branch cut running along ...
Rashad Hamidi, Ben Hoare
doaj +1 more source
Testing dark energy models in the light of $$\sigma _8$$ σ8 tension
It has been pointed out that there exists a tension in $$\sigma _8-\varOmega _m$$ σ8-Ωm measurement between CMB and LSS observation. In this paper we show that $$\sigma _8-\varOmega _m$$ σ8-Ωm observations can be used to test the dark energy theories. We
Gaetano Lambiase +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
We consider a class of ansätze for the construction of exact solutions of the Einstein-nonlinear σ-model system with an arbitrary cosmological constant in (3+1) dimensions.
Alex Giacomini, Marcello Ortaggio
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Nontriviality of the linear sigma model [PDF]
We consider techniques (based on an ultraviolet cutoff) used to prove that the pure boson ($ϕ^4)_4$ field theory is trivial and apply them instead to the dynamically generated quark-level linear sigma model. This cutoff approach leads to the conclusion that the latter field theory is in fact nontrivial.
Babukhadia, L. R., Scadron, M. D.
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Clinical scholarship resource paper [PDF]
The task force conceived this publication as a means of communicating its deliberations to the wider membership of Sigma Theta Tau and the profession. It is intended less as a definitive statement on clinical scholarship and more as a work-in-progress ...
Sigma Theta Tau International
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