Results 91 to 100 of about 847,218 (303)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Topological massive sigma models [PDF]
20 pages, Phyzzx. Revised version to appear in Nucl. Phys. B.
openaire +3 more sources
Integrable coupled sigma-models [PDF]
5 pages, examples ...
Delduc, Francois +3 more
openaire +3 more sources
Unitary models in two dimensions [PDF]
Unitary models in two dimensions are classes of low dimensional theories which provide us with a convenient theoretical laboratory for studying various aspects of the theory of elementary particles.
Zait, R.A, Zait, Reda A.
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A brief review of supersymmetric non-linear sigma models and generalized complex geometry [PDF]
summary:This is a review of the relation between supersymmetric non-linear sigma models and target space geometry. In particular, we report on the derivation of generalized Kähler geometry from sigma models with additional spinorial superfields.
Lindström, Ulf, Ulf Lindström
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Objective To apply biological variation and six Sigma models to evaluate analysis performance of 6 HbA1c analyzers and design the new quality control strategy.Method We collected data of imprecision and inaccuracy from routine internal quality control ...
Xia Wang +4 more
doaj +1 more source
Sigma models with non-commuting complex structures and extended supersymmetry
summary:We discuss additional supersymmetries for $\mathcal{N}=(2,2)$ supersymmetric non-linear sigma models described by left and right semichiral ...
Lindström, U. +3 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

