Results 111 to 120 of about 7,711,295 (297)
Solitons in low-dimensional sigma models [PDF]
, 1997 The aim of this thesis is to study topological soliton solutions in classical field theories, called sigma models, on a three-dimensional space. In chapter 1 we review the general field-theoretical framework of classical soliton solutions and exemplify ...
Gladikowski, J., Gladikowski, Jens
core
Topological defects in K3 sigma models
Journal of High Energy PhysicsWe consider the topological defect lines commuting with the spectral flow and the N $$ \mathcal{N} $$ = (4, 4) superconformal symmetry in two dimensional non-linear sigma models on K3.
Roberta Angius +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Nil-equivariant tropological sigma models on filtered geometries
Journal of High Energy PhysicsWe investigate the behavior of tropological (tropical topological) sigma models on higher dimensional target spaces and show that higher dimensional spaces explicitly admit nested Maslov dequantizations which lead to nontrivial anisotropic filtration ...
Emil Albrychiewicz +2 more
doaj +1 more source
Quantum distillation of Hilbert spaces, semi-classics and anomaly matching
Journal of High Energy Physics, 2018 A symmetry-twisted boundary condition of the path integral provides a suitable framework for the semi-classical analysis of nonperturbative quantum field theories (QFTs), and we reinterpret it from the viewpoint of the Hilbert space. An appropriate twist
Gerald V. Dunne +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Resource paper and position statement on: Leadership and leadership development priorities [PDF]
, 2005 The Honor Society of Nursing, Sigma Theta Tau International has long recognized and supported the importance of leadership and leadership development in the nursing profession.
Sigma Theta Tau International
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A novel symmetry in sigma models [PDF]
Physics Letters B, 1996 A class of non-linear sigma models possessing a new symmetry is identified. The same symmetry is also present in Chern-Simons theories. This hints at a possible topological origin for this class of sigma models. The non-linear sigma models obtained by non-Abelian duality are a particular case in this class.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source