Results 171 to 180 of about 47,123 (262)

A prescription‐free, radiobiology‐based framework for automated VMAT planning: A feasibility study in primary prostate cancer radiotherapy

Medical Physics, Volume 53, Issue 3, March 2026.
Abstract Background Current VMAT planning workflows for prostate cancer primarily depend on conventional dose–volume criteria specified at discrete dose or volume points. These point‐based objectives, however, do not necessarily lead to globally optimal, patient‐specific treatment plans.
Dejan Kuhn, Simon K. B. Spohn, Constantinos Zamboglou, Anca‐Ligia Grosu, Dimos Baltas, Ilias Sachpazidis   +5 more
wiley   +1 more source

Population PK/PD Modeling for Evaluation of Intertwining Effects of Drug and Disease on Thrombocytopenia in Acute Leukemias

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT In hematological malignancies, thrombocytopenia is a frequent feature of the disease. Anti‐leukemic therapies are known to impact thrombocytopenia, which is commonly selected as a dose‐limiting toxicity in early clinical trials. However, given the concurrent myelosuppressive effects of the drug and the underlying leukemia, it can be difficult ...
Tomás Sou, Kamel Malek, Hans‐Jochen Weber   +2 more
wiley   +1 more source

Modeling Polymeric Drug Release: The Emerging Role of Machine Learning

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.
A review of mechanistic, empirical, and machine learning (ML) approaches for modeling drug release from polymeric systems, highlighting how data‐driven methods uncover relationships between formulation parameters and release behavior to guide future drug delivery design.
Ryan N. Woodring, Kristy M. Ainslie
wiley   +1 more source

Comprehension of rectosigmoid junction cancer molecular features by comparison to the rectum or sigmoid colon cancer. [PDF]

J Gastrointest Oncol, 2023
Zhu Q, Zhu C, Zhang X, Zhu X, Chen Z, Gu D, He Y, Jin C.   +7 more
europepmc   +1 more source

Label Noise in Pathological Segmentation Is Overlooked, Leading to Potential Overestimation of Artificial Intelligence

Cancer Science, Volume 117, Issue 3, Page 852-863, March 2026.
This study evaluated how artificial label noise affects cancer pathology segmentation models, demonstrating that boundary‐dependent noise leads to overestimation of performance metrics, while random noise mixtures further harm generalization. Our results highlight the need for standardized noise‐quantification and mitigation methods and for developing ...
Kenji Harada, Yuichiro Nomura, Daisuke Komura, Shumpei Ishikawa, Shingo Sakashita   +4 more
wiley   +1 more source

Robotic-Assisted Sigmoidectomy with D3 Lymphadenectomy for Sigmoid Colon Cancer in a Patient with Situs Inversus Totalis: A Case Report. [PDF]

Surg Case Rep
Minami K, Kawano S, Furukawa T, Tsutsui Y, Kimura K, Nobutou Y, Yano H, Kajiwara Y, Minagawa R, Nishizaki T.   +9 more
europepmc   +1 more source

Management of Pregnancy and Delivery After Augmentation Cystoplasty: A Novel Surgical Technique Using the Sigmoid Colon With Retroperitoneal Mesentery Placement Optimized for Cesarean Section

International Journal of Urology, Volume 33, Issue 3, March 2026.
ABSTRACT Objectives To examine pregnancy and delivery outcomes in women who underwent sigmoid colon cystoplasty with retroperitoneal mesentery placement, a novel surgical technique designed to reduce cesarean section (CS) complications. Methods A retrospective review at three institutions identified women who conceived after augmentation cystoplasty ...
Atsuko Sato, Hiroshi Asanuma, Mizuki Izawa, Shun Iwasa, Taiju Hyuga, Hiroyuki Satoh, Kimihiko Moriya, Hideo Nakai, Mototsugu Oya   +8 more
wiley   +1 more source

Endoscopic submucosal dissection with a traction-guided rendezvous approach for sigmoid colon cancer in the distal limb of a double-barrel colostomy. [PDF]

Endoscopy
Hayashi A, Chiba H, Hirohata A, Iida T, Ebisawa Y, Arimoto J, Nakaoka M.   +6 more
europepmc   +1 more source

Sintilimab-induced erythema multiforme drug eruption in the treatment of sigmoid colon cancer: A case report and literature review. [PDF]

Medicine (Baltimore), 2023
Zhang M, Wu R, Jia M, Sun S, Zhang L, Tang T.   +5 more
europepmc   +1 more source

Reirradiation for Recurrent Cervical Cancer Within the Previous Radiation Field Using a Bioabsorbable Spacer: A Case Report

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 3, March 2026.
ABSTRACT Reirradiation for cervical cancer recurrence in previously irradiated fields is challenging due to dose limitations. To our knowledge, this is the first case report describing successful reirradiation using a bioabsorbable spacer for vaginal cuff recurrence after initial concurrent chemoradiotherapy (CCRT) and hysterectomy. A 70‐year‐old woman
Yusuke Matoba, Yuriko Oomori, Ikuno Nishibuchi, Shinnosuke Uegami, Kosuke Nakamoto, Takuto Uyama, Katsuyuki Tomono, Suguru Nosaka, Hiroki Ohge, Shinya Takahashi, Yuji Murakami, Ken Yamaguchi, Kouji Banno   +12 more
wiley   +1 more source