Results 161 to 170 of about 38,470 (308)

Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome

open access: yesInternational Journal of Cancer, Volume 157, Issue 6, Page 1154-1167, 15 September 2025.
What's new? Serrated polyposis syndrome has been associated with an increased risk of colorectal cancer. HIC1 is a tumor suppressor gene commonly silenced in serrated polyps and several cancers. This study suggests HIC1 as a novel germline predisposition factor to serrated polyposis syndrome, with variants altering gene transcriptional regulation and ...
Xavier Domínguez‐Rovira   +24 more
wiley   +1 more source

Idiopathic Myointimal Hyperplasia of the Mesenteric Veins: Diagnosed After Resection due to Insufficient Palliative Surgery. [PDF]

open access: yesSurg Case Rep
Hoshino N   +9 more
europepmc   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai   +6 more
wiley   +1 more source

The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population‐based cohort study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard   +8 more
wiley   +1 more source

Uterine “twisting sign”: A new potential ultrasonographic soft marker for deep endometriosis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The objective of the current study was to evaluate the “twisting sign,” defined as uterine fundus rotation observed on transvaginal sonography (TVS), as a potential soft marker for deep endometriosis (DE) and its association with specific DE localizations and indirect signs.
Fabio Barra   +7 more
wiley   +1 more source

Atypical bilateral papilledema during the puerperium: a case report. [PDF]

open access: yesFront Med (Lausanne)
Jiang L   +5 more
europepmc   +1 more source

PMAT2: An efficient graphical assembly toolkit for comprehensive organellar genomes

open access: yesiMeta, EarlyView.
We developed PMAT2, an advanced toolkit for lineage‐specific de novo assembly of plant, animal, and fungal mitochondrial genomes, as well as plant chloroplast genome. PMAT2 leverages optimized graph‐based strategies tailored to organelle genome complexity, enabling complete and accurate assemblies, even with approximately 1 × highly accurate PacBio ...
Fuchuan Han   +10 more
wiley   +1 more source

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