Results 171 to 180 of about 9,106,328 (402)

Invitation for FOBt screening and colorectal cancer mortality: A prospective analysis in the Million Women Study cohort

open access: yesInternational Journal of Cancer, EarlyView.
The screening effectiveness of population screening programmes can differ from the screening efficacy measured in randomised controlled trials and is often difficult to measure directly. The authors used data on a subset of women born between 1935 and 1939 from the Million Women Study to estimate the effect of screening on colorectal cancer mortality ...
Roger G. Blanks   +2 more
wiley   +1 more source

Triple-Stream Deep Feature Selection with Metaheuristic Optimization and Machine Learning for Multi-Stage Hypertensive Retinopathy Diagnosis [PDF]

open access: yesarXiv
Hypertensive retinopathy (HR) is a severe eye disease that may cause permanent vision loss if not diagnosed early. Traditional diagnostic methods are time-consuming and subjective, highlighting the need for an automated, reliable system. Existing studies often use a single Deep Learning (DL) model, struggling to distinguish HR stages.
arxiv  

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini   +18 more
wiley   +1 more source

Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Serrated polyposis syndrome has been associated with an increased risk of colorectal cancer. HIC1 is a tumor suppressor gene commonly silenced in serrated polyps and several cancers. This study suggests HIC1 as a novel germline predisposition factor to serrated polyposis syndrome, with variants altering gene transcriptional regulation and ...
Xavier Domínguez‐Rovira   +24 more
wiley   +1 more source

Fine-Grained ECG-Text Contrastive Learning via Waveform Understanding Enhancement [PDF]

open access: yesarXiv
Electrocardiograms (ECGs) are essential for diagnosing cardiovascular diseases. While previous ECG-text contrastive learning methods have shown promising results, they often overlook the incompleteness of the reports. Given an ECG, the report is generated by first identifying key waveform features and then inferring the final diagnosis through these ...
arxiv  

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai   +6 more
wiley   +1 more source

Phase-shifted remote photoplethysmography for estimating heart rate and blood pressure from facial video [PDF]

open access: yesarXiv
Human health can be critically affected by cardiovascular diseases, such as hypertension, arrhythmias, and stroke. Heart rate and blood pressure are important biometric information for the monitoring of cardiovascular system and early diagnosis of cardiovascular diseases.
arxiv  

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