Results 171 to 180 of about 38,470 (308)

Can Methotrexate Monotherapy Achieve Clinical Remission in Patients with Active Rheumatoid Arthritis? A Model‐Based Meta‐Analysis

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study utilized model‐based meta‐analysis (MBMA) to systematically assess the efficacy of methotrexate (MTX) monotherapy in improving rheumatoid arthritis (RA) symptoms and function. The assessment was based on indicators such as Disease Activity Score 28 (DAS28), Health Assessment Questionnaire, and American College of Rheumatology (ACR ...
Shengyang Chen   +5 more
wiley   +1 more source

The host genes influencing <i>Clostridioides difficile</i> infection and the potential role of intestinal Lactobacillus acidophilus: a Mendelian randomization and animal model study. [PDF]

open access: yesFront Cell Infect Microbiol
Sun Y   +13 more
europepmc   +1 more source

Characterizing Cellular Expansion of Idecabtagene Vicleucel and Association with Clinical Efficacy and Safety in Patients with Triple‐Class‐Exposed Relapsed/Refractory Multiple Myeloma

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Idecabtagene vicleucel (ide‐cel, ABECMA) is an autologous, B‐cell maturation antigen‐directed, chimeric antigen receptor (CAR) T‐cell therapy, which has demonstrated significantly improved progression‐free survival (PFS) and overall response rate (ORR) in patients with triple‐class‐exposed relapsed/refractory multiple myeloma (TCE RRMM). Here,
Fan Wu   +11 more
wiley   +1 more source

Rectosigmoid endometriosis, a rare cause of lower GI bleeding in a premenopausal woman: Case report. [PDF]

open access: yesInt J Surg Case Rep
Sumbizi C   +5 more
europepmc   +1 more source

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

Point‐of‐care ultrasound provides useful information in children with Crohn's disease visiting the outpatient clinic

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Point‐of‐care ultrasound (POCUS) is increasingly used in clinical practice. However, it's additional value next to conventional markers of disease activity has not been studied in paediatric Crohn's disease (CD). This study aimed to assess the clinical added value of POCUS in children with CD.
Elsa A. van Wassenaer   +7 more
wiley   +1 more source

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