Results 41 to 50 of about 28,227 (259)

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

BARD1 deletion in a patient with suspected hereditary colorectal cancer

Human Genome Variation
Deleterious germline variants in the BRCA1-associated ring domain (BARD1) gene moderately elevate breast cancer risk; however, their potential association with other neoplasms remains unclear.
Nobue Takaiso, Issei Imoto, Akiyo Yoshimura, Akira Ouchi, Koji Komori, Hiroji Iwata, Yasuhiro Shimizu   +6 more
doaj   +1 more source

Hemipelvectomia externa ampliada para tratar adenocarcinoma de sigmóide

Revista do Colégio Brasileiro de Cirurgiões
Surgery is the most effective way of treating a locally advanced colorectal carcinoma and an extended en bloc resection is necessary to achieve the best overall survival rate.
Rodrigo Ribas Dias dos Reis, Luciane Schiavinatto, Mário Luis Telles, Adriana Eliza Brasil Moreira, João Paulo Aguiar Jordão Mainardi   +4 more
doaj   +1 more source

A Colonic Perineurioma

Clinical Medicine Insights: Pathology, 2018
Perineurioma is a mesenchymal neoplasm best known in soft-tissue pathology. A colonic perineurioma is a relatively recently described entity and sometimes encountered in specimens from the large intestine, especially distal colon. Without its recognition,
Tomoyuki Otani, Kinta Hatakeyama, Emi Ohtani, Susumu Nakayama, Takashi Fujimoto, Chiho Ohbayashi   +5 more
doaj   +1 more source

Efficacy of endoscopic surveillance in the detection of local recurrence after radical rectal cancer surgery is limited? A retrospective study

World Journal of Surgical Oncology, 2021
Background Rectal cancer, one of most common neoplasms, is characterized by an overall survival rate exceeding 60%. Nonetheless, local recurrence (LR) following surgery for rectal cancer remains a formidable clinical problem. The aim of this study was to
Michal Jankowski, Wojciech M. Wysocki, Manuela Las-Jankowska, Karol Tkaczyński, Dorian Wiśniewski, Dariusz Bała, Wojciech Zegarski   +6 more
doaj   +1 more source

A CASE OF COMPOSITE GOBLET CELL CARCINOID-ADENOCARCINOMA NEOPLASM OF THE SIGMOID COLON

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2007
症例は76歳, 男性. 腹部膨満感を主訴に当院を受診した. 腹部X線検査, 腹部CT検査にてS状結腸癌による大腸イレウスが疑われ, 人工肛門造設術を施行した. その後大腸内視鏡検査を行い, 病変部の病理組織検査にてカルチノイドが疑われS状結腸切除, D2郭清を施行した. 病理組織学的にS状結腸の病変は, 杯細胞カルチノイドと腺癌の混合腫瘍であった. 術後1年経過した現在, 再発なく生存中である. 杯細胞カルチノイドはそのほとんどが虫垂に発生し, 虫垂以外での報告は極めて稀である. また本症例は同一腫瘍内にカルチノイドと腺癌が合併していた. 杯細胞カルチノイドや腺癌の組織発生を考える上で興味深い症例であると考えられた. 若干の文献的考察を加えて報告する.
Norifumi HATTORI, Katsumi KOSHIKAWA, Masaki WADA, Kenji TANIGUCHI, Hiroyuki YOKOYAMA, Hiroyuki SUENAGA   +5 more
openaire   +2 more sources

Perioperative and Oncological Outcomes of Colorectal Cancer Surgery in Obese Patients: A Multicenter Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
The prognostic value of the log odds of positive lymph nodes (LODDS) across BMI categories was investigated in patients undergoing colorectal cancer resection. The exploratory evidence demonstrates that LODDS serves as a strong prognostic marker, and its adverse effect may be more pronounced in patients with higher BMI.
Kazuhiro Taguchi, Manabu Shimomura, Wataru Shimizu, Satoshi Ikeda, Masanori Yoshimitsu, Mohei Kouyama, Masahiro Nakahara, Hironori Kobayashi, Masatoshi Kochi, Yosuke Shimizu, Daisuke Sumitani, Shoichiro Mukai, Yuji Takakura, Yasuyo Ishizaki, Shinya Kodama, Masahiko Fujimori, Hiroshi Okuda, Takuya Yano, Tomoaki Bekki, Atsuhiro Watanabe, Saki Sato, Toshiyuki Moriuchi, Shohei Shiozaki, Kazuki Matsubara, Mizuki Yamaguchi, Tomohiro Adachi, Sho Ishikawa, Hideki Ohdan   +27 more
wiley   +1 more source

Low‐grade appendiceal mucinous neoplasm penetrating sigmoid colon: A case report

Asian Journal of Endoscopic Surgery
AbstractLow‐grade appendiceal mucinous neoplasm (LAMN) is principally characterized by low‐grade cytology without evidence of invasion to other organs. We report a LAMN surgical case whose appendiceal tumor penetrated the sigmoid colon wall. An 87‐year‐old man was referred for endoscopic resection (ER) of a colon polyp.
Michio Okamoto, Ryosuke Okamura, Yoshiro Itatani, Yuki Aisu, Hiromitsu Kinoshita, Nobuaki Hoshino, Hisatsugu Maekawa, Takashi Sakamoto, Keiko Kasahara, Shintaro Okumura, Tatsuto Nishigori, Shigeo Hisamori, Shigeru Tsunoda, Koya Hida, Mitsuhiro Nikaido, Yukiko Hiramatsu, Yuki Teramoto, Satoshi Nagayama, Kazutaka Obama   +18 more
openaire   +3 more sources

Thin occlusive syndrome due to sigmoid neoplasm

, 2020
Presentado en sesión de 25 de mayo de 1953 
Zerboni, Eugenio R, Ardao, Alberto
openaire   +1 more source

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source