Results 1 to 10 of about 19,161 (223)

Routine Sigmoidoscopy--An Evaluation [PDF]

open access: yesCa-A Cancer Journal for Clinicians, 1967
A H Letton
exaly   +3 more sources

A case report of Peutz–Jeghers syndrome in a child with Crohn's disease

open access: yesJPGN Reports, EarlyView.
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu   +5 more
wiley   +1 more source

Pediatric Clostridiodes difficile infection with toxic megacolon successfully treated with fecal microbiota transplantation

open access: yesJPGN Reports, EarlyView.
Abstract The rising incidence of pediatric Clostridioides difficile infection (CDI), particularly in medically complex patients, calls for novel, individualized treatments. While fecal microbiota transplantation (FMT) is well‐described for recurrent CDI, this report describes the first pediatric case of fulminant CDI with toxic megacolon successfully ...
Dana McCarney   +3 more
wiley   +1 more source

Endoscopic findings in patients with Shwachman–Diamond syndrome: A report from the North American Shwachman–Diamond syndrome registry

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn   +15 more
wiley   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski   +7 more
wiley   +1 more source

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons   +8 more
wiley   +1 more source

Green Endoscopy: Can Filtered Water Use in Endoscopy Be a Safe, Economical Alternative Which Promotes Sustainable Healthcare?

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Sustainable healthcare is an evolving paradigm of growing importance that focuses on reducing environmental impact whilst maintaining quality patient care. Currently, evidence is lacking to support the use of sterile water in diagnostic colonoscopy resulting in a growing shift towards use of tap water and appropriate recycling of ...
Michael Rouse   +6 more
wiley   +1 more source

Seven Years of Watch and Wait With Rectal Cancer—Reflections and Optimisations

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Purpose Sir Charles Gairdner Hospital (SCGH) commenced an observation strategy in patients with a complete clinical response, Watch and Wait (W&W), for rectal adenocarcinoma in 2017 using a rigorous surveillance protocol. Our earlier results (2017–2019) have been published.
Ben Finlay   +5 more
wiley   +1 more source

Does Local Excision Without Salvage Surgery Affect the Prognostic Outcome of Patients With Malignant Colorectal Polyp? A Long‐Term Survival Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Management of malignant colorectal polyp has been a treatment dilemma for clinicians. This study aims to evaluate the long‐term survival outcome of patients with and without salvage surgery after local excision. Methods From January 2000 to December 2022, patients with T1 malignant colorectal polyp diagnosed after local ...
Vienna Man Wah Ng   +4 more
wiley   +1 more source

Rates of hypoglycemia and electrolyte abnormalities in children presenting for endoscopy in a tertiary hospital

open access: yes
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Rahmath Althaf   +4 more
wiley   +1 more source

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