Results 61 to 70 of about 29,426 (209)

Effectiveness of sigmoidoscopy or colonoscopy screening on colorectal cancer incidence and mortality: a systematic review and meta-analysis of randomized controlled trial

Frontiers in Oncology
ObjectivesWe conducted a comprehensive analysis to compare colonoscopy and sigmoidoscopy with standard care or fecal immunochemistry regarding colorectal cancer incidence and mortality risk.MethodsUntil August 2023, literature from PubMed, Embase, Web of
Chunyang Han, Fan Wu, Jian Xu
doaj   +1 more source

Detection of cancers and advanced adenomas in asymptomatic participants in colorectal cancer screening: a cross-sectional study

BMJ Open, 2021
Objectives To assess detection rates for colorectal cancer (CRC) and advanced adenomas in asymptomatic CRC screening participants and bowel symptoms in association with CRC and advanced adenoma.Design Cross-sectional study.Setting Two screening centres ...
Edoardo Botteri, Thomas de Lange, Øyvind Holme, Geir Hoff, Sigrun Losada Eskeland, Anna Lisa Schult, Kristin R Randel, Eirin Dalén   +7 more
doaj   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Review of economic evidence in the prevention and early detection of colorectal cancer. [PDF]

, 2013
This paper aims to systematically review the cost-effectiveness evidence, and to provide a critical appraisal of the methods used in the model-based economic evaluation of CRC screening and subsequent surveillance.
Cairns, John A, Jeong, Kim E
core   +2 more sources

Modeling the Natural History and Screening Effects of Colorectal Cancer Using Both Adenoma and Serrated Neoplasia Pathways: The Development, Calibration, and Validation of a Discrete Event Simulation Model

MDM Policy & Practice, 2023
Background. Existing colorectal cancer (CRC) screening models mostly focus on the adenoma pathway of CRC development, overlooking the serrated neoplasia pathway, which might result in overly optimistic screening predictions.
Chih-Yuan Cheng, Silvia Calderazzo, Christoph Schramm, Michael Schlander   +3 more
doaj   +1 more source

Gastroenterological disorders and hepatic disease in adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the incidence, prevalence, and prognostic factors for gastroenterological disorders and hepatic disease in adults with cerebral palsy (CP), and to examine the effectiveness of any screening or interventions. Method Six databases were searched for articles published in any language since 1990 meeting eligibility criteria ...
Christina M. Marciniak, Jennifer M. Ryan, Alejandra Camacho‐Soto, Emily Capellari, Jessica Burke, Maram Sofiany, Zoë Post, Eric C. Sung, Michael D. Brown, the Adult Cerebral Palsy Clinical Practice Guidelines Working Group, Jennifer M Ryan, Rachel Byrne, Emily Capellari, Donna Riccio Omichinski, Mark Peterson, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms, Christina M. Marciniak   +18 more
wiley   +1 more source

Immune cell infiltration correlates with intestinal permeability, inflammation, and gastrointestinal symptoms in type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
In individuals with type 1 diabetes, immune cell infiltration in the colon mucosa tended to correlate with fecal and systemic markers of intestinal permeability and inflammation, as well as gastrointestinal symptoms. These findings suggest that low‐grade gut immune activation might link the intestinal barrier dysfunction with systemic endotoxin ...
Polina Zalizko, Reinis Isaks, Leonora Pahirko, Aleksejs Fedulovs, Eduards Krustins, Jurijs Nazarovs, Sergejs Dubencovs, Hanne Salmenkari, Markku Lehto, Kaspars Jēkabsons, Una Riekstiņa, Per‐Henrik Groop, Niina Sandholm, Jeļizaveta Sokolovska   +13 more
wiley   +1 more source

Exploring Associations of Different Types of Childhood Trauma With Symptomatology in Irritable Bowel Syndrome

Neurogastroenterology &Motility, EarlyView.
The current cross‐sectional study aimed to elucidate the impact of different types of childhood trauma on IBS symptomatology. Our findings strongly support the significant role of childhood trauma in IBS pathology and indicate the specific relevance of emotional abuse influencing not only gastrointestinal symptoms but also extraintestinal and ...
Tetyana Bureychak, Jenny Sjödahl, Nawroz Barazanji, Gustav Orell, Olivia Book, Rozalyn Simon, Olga Bednarska, Adriane Icenhour, Susanna Walter   +8 more
wiley   +1 more source

An immunocompromised dialysis patient with skin and bone lesions [PDF]

, 2010
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown, Griffith, Jarzembowski, Katoch, Swenson, Uslan, Wallace, Wallace   +7 more
core   +2 more sources

Recent advancement in daignosis of gastrointestinal diseases

Journal of Applied Pharmaceutical Research, 2015
Gastrointestinal diseases refer to ulcerative disorders of the upper gastrointestinal tract. Stomach acids and some enzymes can damage the lining of the G.I. tract if natural protective factors are not functioning normally.
Pranit Saraswat, Pragati Khare, Ritesh Tiwari   +2 more
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