Results 31 to 40 of about 91,659 (256)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Multiple positive solutions for Kirchhoff problems with sign-changing potential
Electronic Journal of Differential Equations, 2015 In this article, we study the existence and multiplicity of positive solutions for a class of Kirchhoff type equations with sign-changing potential. Using the Nehari manifold, we obtain two positive solutions.
Gao-Sheng Liu +3 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Ground States for Nonlinear Schrödinger Equations with a Sign-changing Potential Well
Advanced Nonlinear Studies, 2015 Abstract In this paper, we consider the ground state solutions for a class of nonlinear Schrödinger equations where 2 < p < 2*. We investigate the case λ > inf σ (−Δ + V), i.e., an indefinite problem.
Wang, Zhi-Qiang, Xia, Jiankang
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Groundstates of the Choquard equations with a sign-changing self-interaction potential [PDF]
Zeitschrift für angewandte Mathematik und Physik, 2018 We consider a nonlinear Choquard equation $$ -Δu+u= (V * |u|^p )|u|^{p-2}u \qquad \text{in }\mathbb{R}^N, $$ when the self-interaction potential $V$ is unbounded from below. Under some assumptions on $V$ and on $p$, covering $p =2$ and $V$ being the one- or two-dimensional Newton kernel, we prove the existence of a nontrivial groundstate solution $u\in
Luca Battaglia, Jean Van Schaftingen
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 2014 In this article we consider the quasilinear Schrodinger equation where the potential is sign-changing. We employ a mountain pass argument without compactness conditions to obtain the existence of a nontrivial solution.
Xiang-Dong Fang, Zhi-Qing Han
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Boundary Value Problems, 2020 In this paper, we study the following elliptic boundary value problem: { − Δ u + V ( x ) u = f ( x , u ) , x ∈ Ω , u = 0 , x ∈ ∂ Ω , $$ \textstyle\begin{cases} -\Delta u+V(x)u=f(x, u),\quad x\in \Omega , \\ u=0, \quad x \in \partial \Omega , \end{cases} $
Wei He, Qingfang Wu
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Properties of fractional p-Laplace equations with sign-changing potential
Nonlinear AnalysisIn this paper, we consider the nonlinear equation involving the fractional p-Laplacian with sign-changing potential. This model draws inspiration from De Giorgi Conjecture. There are two main results in this paper. Firstly, we obtain that the solution is radially symmetric within the bounded domain, by applying the moving plane method.
Yubo Duan, Yawei Wei
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source