Results 41 to 50 of about 10,457,446 (242)
In this paper we are concerned with the existence of infinitely-many solutions for fractional Hamiltonian systems of the form tD∞α(-∞Dtαu(t))+L(t)u(t)=∇W(t,u(t))${\,}_tD^{\alpha }_{\infty }(_{-\infty }D^{\alpha }_{t}u(t))+L(t)u(t)=\nabla W(t,u(t ...
Zhang Ziheng, Yuan Rong
doaj +1 more source
The purpose of this paper is to study the existence of sign-changing solution to the following fourth-order equation: 0.1 Δ 2 u − ( a + b ∫ R N | ∇ u | 2 d x ) Δ u + V ( x ) u = K ( x ) f ( u ) in R N , $$ \Delta ^{2}u- \biggl(a+ b \int _{\mathbb{R}^{N}}
Wen Guan, Hua-Bo Zhang
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Existence and blow up of small-amplitude nonlinear waves with a sign-changing potential [PDF]
We study the nonlinear wave equation with a sign-changing potential in any space dimension. If the potential is small and rapidly decaying, then the existence of small-amplitude solutions is driven by the nonlinear term.
Karageorgis, Paschalis +1 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In order to expound the influence of sign-changing potential on logarithmic nonlinearity and Hatree nonlinearity. By the variational method, a weak solution to the problem is a critical point of the energy functional. Then, by the logarithmic inequality,
Jianwei HAO, Yongyan HUANG
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Synthesis and evaluation of glycomimetic antagonists for the lectins DC-SIGN and FimH [PDF]
Lectins are carbohydrate-binding proteins that are widely spread in nature and crucially involved in a multitude of biological processes. This thesis addresses the design of glycomimetic antagonists for the human lectin DC-SIGN (chapter 2) and the ...
Mayer, Katharina
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
In this paper, by applying a nonlinear alternative principle of Leray–Schauder and Guo–Krasnosel’skii fixed point theorem on compression and expansion of cones, together with truncation technique, we study the existence of multiplicity noncollision ...
Shengjun Li, Fang Zhang
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

