Results 61 to 70 of about 91,659 (256)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Multiplicity of solutions for a singular system with sign-changing potential
Forum MathematicumAbstract This paper focuses on a singular system with a sign-changing potential in Γ, a bounded domain with a Lipschitz boundary in ℝ d
Lin, Wentao, Wei, Yilan
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The fractional Schrödinger equation with Hardy-type potentials and sign-changing nonlinearities [PDF]
Nonlinear Analysis, 2018 We look for solutions to a fractional Schrödinger equation of the following form $$ (-Δ)^{α/ 2} u + \left( V(x) - \fracμ{|x|^α} \right) u = f(x,u)-K(x)|u|^{q-2}u\hbox{ on }\mathbb{R}^N \setminus \{0\}, $$ where $V$ is bounded and close-to-periodic potential and $- \fracμ{|x|^α}$ is a Hardy-type potential.
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Electronic Journal of Differential Equations, 2017 In this article, we prove the existence of infinitely many solutions for the fractional $p$-Laplacian equation $$ (-\Delta)^s_p u+V(x)|u|^{p-2}u=f(x,u),\quad x\in \mathbb{R}^N $$ where $s\in(0,1)$, $2\leq ...
Youpei Zhang, Xianhua Tang, Jian Zhang
doaj
Computers & Mathematics with Applications, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hongliang Liu +2 more
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FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Infinitely many solutions for elliptic boundary value problems with sign-changing potential
Electronic Journal of Differential Equations, 2014 In this article, we study the elliptic boundary value problem $$\displaylines{ -\Delta u+a(x)u=g(x, u) \quad \text{in } \Omega,\cr u = 0\quad \text{on } \partial \Omega, }$$ where $ \Omega\subset \mathbb{R}^N$ $(N\geq3)$ is a bounded domain with
Wen Zhang, Xianhua Tang, Jian Zhang
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Advances in Difference Equations, 2020 This paper is concerned with the following system: { − Δ u + λ A ( x ) u − K ( x ) ( 2 ω + ϕ ) ϕ u = f ( x , u ) + h ( x ) , x ∈ R 3 , Δ ϕ = K ( x ) ( ω + ϕ ) u 2 , x ∈ R 3 , $$ \textstyle\begin{cases} {-\Delta u+\lambda A(x) u-K(x)(2 \omega +\phi ) \phi
Canlin Gan, Ting Xiao, Qiongfen Zhang
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