Results 61 to 70 of about 173,627 (309)

A video coding system for sign language communication at low bit rates [PDF]

open access: yes, 2004
The ability to communicate remotely through the use of video as promised by wireless networks and already practised over fixed networks, is for deaf people as important as voice telephony is for hearing people. Sign languages are visual-spatial languages
Kyle, J   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Development of sign language for young children [PDF]

open access: yes, 2006
Plan AThe Child and Family Study Center (CFSC) serves as a laboratory school and observation site for Early Childhood Education Majors and other related majors on campus.
Barnhart, Lindsay J.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The relationship between deaf and hard of hearing students' Japanese Sign Language and Japanese Language Proficiency [PDF]

open access: yes, 2009
The present study represents an attempt to investigate the relationship between Japanese Sign Language proficiency and the Japanese literacy skills of high school students who are deaf or hard or hearing (D/HH). A Pilot Test of Japanese Sign Language was
Fordyce, Mariela
core  

Eye gaze in creative sign language

open access: yes, 2013
This article discusses the role of eye gaze in creative sign language. Because eye gaze conveys various types of linguistic and poetic information, it is an intrinsic part of sign language linguistics in general and of creative signing in particular.
Kaneko, Michiko, Mesch, Johanna,
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

American Sign Language Club

open access: yes, 2021
The purpose of American Sign Language (ASL) Club is to get club members comfortable with signing an introduction of why they are and where they come from in order to feel prepared to engage in conversation with deaf or hard of hearing ...
American Sign Language Club, University of Maine
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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