Results 61 to 70 of about 4,182,380 (246)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The relationship between deaf and hard of hearing students' Japanese Sign Language and Japanese Language Proficiency [PDF]

, 2009
The present study represents an attempt to investigate the relationship between Japanese Sign Language proficiency and the Japanese literacy skills of high school students who are deaf or hard or hearing (D/HH). A Pilot Test of Japanese Sign Language was
Fordyce, Mariela
core  

Sign Language, Hawaiian

, 2016
Hawaii Sign Language (HSL) is a language used by approximately 40 individuals in the Hawaiian Islands. All of the known users are older and primarily use American Sign Language (ASL), making HSL a critically endangered language.
Lambrecht, Linda, Rarrick, Samantha
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The Interpreters' Newsletter 19, Sign Language Interpreting

, 2014
This issue of The Interpreters’ Newsletter aims to address a number of topics of interest in this growing area of Interpreting Studies presented in the form of discussion on prevailing situations, personal impressions on the profession (e.g.
Schaumberger Elke, Freelance Sign Language interpreter, Napier Jemina, Heriot Watt University, de Wit Maya, Freelance Sign Language interpreter, Swabey Laurie, S. t. Catherine University, Sluis Irma, Freelance Sign Language interpreter, Wang Jihong, Macquarie University, Alley Erica, S. t. Catherine University, Kellett, CYNTHIA JANE MARY, Nicodemus Brenda, Gallaudet University, Kellett C.J, Shaw Sherry, University of North Florida, Taylor Marty M., Interpreting Consolidated, Brück Patricia, Freelance Sign Language interpreter   +12 more
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Building a sign language corpus for use in machine translation [PDF]

, 2010
In recent years data-driven methods of machine translation (MT) have overtaken rule-based approaches as the predominant means of automatically translating between languages.
Harold Somers, Ipan D, Morrissey, Sara, Robert Smith, Somers, Harold, Smith, Robert, Sara Morrissey, Shane Gilchrist, Dandapat, Sandipan, Gilchrist, Shane   +9 more
core   +2 more sources

Barriers Faced by Deaf Individuals while Availing Speech and Hearing Services

Auditory and Vestibular Research
Background and Aim: Deaf individuals in India face significant auditory impairment, leading to challenges in accessing services. Studies highlight the need to enhance communication services and accessibility to ensure fair access to resources for the ...
Reuben Thomas Varghese, Rajkumar Rimmalapudi, Rubby Viren, Karthik Venkat Sridaran, Reshma Odungattu, Govindaraju Teja   +5 more
doaj   +1 more source