Results 61 to 70 of about 1,620,823 (329)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Multiplane wave imaging increases signal-to-noise ratio in ultrafast ultrasound imaging

Physics in Medicine and Biology, 2015
Ultrafast imaging using plane or diverging waves has recently enabled new ultrasound imaging modes with improved sensitivity and very high frame rates.
E. Tiran, T. Deffieux, M. Correia, D. Maresca, B. Osmanski, Lim-Anna Sieu, Antoine Bergel, I. Cohen, M. Pernot, M. Tanter   +9 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Harnessing Data-mining Algorithms to Model and Evaluate Factors Influencing Distortion Product Otoacoustic Emission Variations in a Mining Industry

International Journal of Environmental Health Engineering
Aim: The aim of this study was to gauge the condition of otoacoustic emissions (OAEs) in workers, followed by modeling and estimating the weight of factors affecting changes in their emissions. Methods: The present study comprises two main phases. In the
Sajad Zare, Reza Esmaeili, Mojtaba Nakhaei pour   +2 more
doaj   +1 more source

Non-uniformity of Clinical Head, Head and Neck, and Body Coils in Magnetic Resonance Imaging (MRI) [PDF]

Iranian Journal of Medical Physics, 2014
Introduction Signal intensity uniformity in a magnetic resonance (MR) image indicates how well the MR imaging (MRI) system represents an object. One of the major sources of image non-uniformity in high-field MRI scanners is inhomogeneity of radio ...
Mahmood Nazarpoor
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Eddy-covariance data with low signal-to-noise ratio: time-lag determination, uncertainties and limit of detection

, 2015
. All eddy-covariance flux measurements are associated with random uncertainties which are a combination of sampling error due to natural variability in turbulence and sensor noise.
B. Langford, W. Acton, C. Ammann, A. Valach, E. Nemitz   +4 more
semanticscholar   +1 more source

Model Analysis of FDD-LTE Forward Interference and Capacity

Dianxin kexue, 2015
The forward interference is an important factor that affects the FDD-LTE network capacity and user experience. FDD-LTE forward interference and capacity were analyzed. A forward interference model was proposed under various network loads.
Ge Zhou, Junwen Wang
doaj   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source