Results 81 to 90 of about 4,029,563 (257)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Simultaneous Detection of Body Movements Using Nanocomposite Multifunctional Mechanical Wearable Sensor

IET Science, Measurement & Technology
The field of wearable sensors, particularly motion sensors, has experienced noteworthy advancements in recent years. Motion sensors have significantly assisted doctors by gathering real‐time data and transmitting information remotely, proving highly ...
Ahad Mahanfar, Alireza Nikfarjam, Alireza SalavatiMohammadi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Boundary‐Aware Learning for Robust Automatic Modulation Recognition Based on Adaptive Pyramid Network

IET Radar, Sonar & Navigation
Automatic modulation recognition (AMR) of radar signals plays a pivotal role in intelligent spectrum management for modern electronic warfare systems.
Yuanhang Li, Mengyi Qi, Xiaofeng Tao, Wenbin Shao   +3 more
doaj   +1 more source

Hyperspectral images segmentation: a proposal [PDF]

, 2009
Hyper-Spectral Imaging (HIS) also known as chemical or spectroscopic imaging is an emerging technique that combines imaging and spectroscopy to capture both spectral and spatial information from an object. Hyperspectral images are made up of contiguous
GORETTA, Nathalie, CHRISTOPHE, Florio, LELONG, Camille, Fiorio, Christophe, ROGER, Jean-Michel, Gorretta, Nathalie, Bellon Maurel, Véronique, RABATEL, Gilles, BELLON-MAUREL, Véronique   +8 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

MAE‐SigNet: An effective network for automatic modulation recognition

IET Communications
The rapid development of the Internet of Things has exacerbated issues such as spectrum resource scarcity, poor communication quality, and high communication energy consumption. Automatic modulation recognition (AMR), a key technology in cognitive radio,
Shilong Zhang, Yu Song, Shubin Wang
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source