Results 101 to 110 of about 4,029,563 (257)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

MD-Net: A Lightweight Dual-Branch Network with Adaptive Time-Frequency Masking for Robust UAV RF Signal Classification

open access: yesInformation
In the multi-class recognition task for unmanned aerial vehicle (UAV) radio frequency (RF) signals, noise interference and complex backgrounds can significantly degrade recognition performance.
Min Huang, Leihan Dou, Qiuhong Sun
doaj   +1 more source

Partially Supervised Approach in Signal Recognition [PDF]

open access: yes
The paper focuses on the potential of principal directions based approaches in signal classification and recognition. In probabilistic models, the classes are represented in terms of multivariate density functions, and an object coming from a certain ...
Doru CONSTANTIN   +3 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Design and Evaluation of a Compact CNN for EMG-Based Wearable Systems Under Embedded Constraints

open access: yesSensors
Electromyographic (EMG) signals are increasingly used in wearable cyber–physical systems (CPS), where reliable movement recognition must be achieved under limited computational resources.
Valentina Tirsu   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Evaluation of Support Vector Machine and Random Forest Models for EMG-Based Knee Motion Phase Classification

open access: yesIEEE Access
Knee-related conditions, such as anterior cruciate ligament injuries and meniscal ruptures, significantly affect mobility and quality of life. Although range-of-motion exercises are important for rehabilitation, interpreting electromyography signals ...
Ing Teck Phang   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Multi‐view synergistic enhanced fault recording data for transmission line fault classification

open access: yesIET Communications
Fault recorded data has been proven to be effective for fault diagnosis of overhead transmission lines. Utilizing deep learning to mine potential fault patterns in fault recording data is an inevitable trend.
Minghui Jia   +9 more
doaj   +1 more source

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