Results 61 to 70 of about 2,880,447 (285)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Validation by Measurements of a IC Modeling Approach for SiP Applications [PDF]

open access: yes, 2011
The growing importance of signal integrity (SI) analysis in integrated circuits (ICs), revealed by modern systemin-package methods, is demanding for new models for the IC sub-systems which are both accurate, efficient and extractable by simple ...
Teixeira, H.M.   +20 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Pathway to Ultra-Fast Data Transmission for Next-Generation Networks through Terahertz Communication in 6G [PDF]

open access: yesIranian Journal of Information Processing & Management
Background: As the demand for ultra-fast, low-latency communication continues to rise, Terahertz (THz) communication has emerged as a promising candidate for enabling next-generation 6G networks. However, environmental sensitivity and hardware challenges
Sura Sabah   +4 more
doaj   +1 more source

Signal integrity analysis and Peripheral Component Interconnect Express backplane link compliance assessment

open access: yesEngineering Reports, 2022
This article presents research conducted on the backplane high‐speed Peripheral Component Interconnect Express version 4 (PCIe gen4) link between central processor root complex and the end‐point device in order to confirm its compliance. Signal integrity
Evgeny Orekhov   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Audio Signal Authentication and Integrity Protection

open access: yesComputers
This paper presents SAIN (Signal Authentication and INtegrity), an improvement to an algorithm developed for the fragile watermarking of audio files, composed of sequences of samples, with the purpose of integrity protection.
Marco Botta   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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