Results 41 to 50 of about 509,648 (256)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Integration of light and hormone signals [PDF]
Plant Signaling & Behavior, 2008 After germination, seedlings follow one of two developmental programs, photo- and skotomorphogenesis, and the choice is determined by the interplay between environmental signals (light) and endogenous cues (the plant hormones gibberellins among others). In the December issue of Plant Journal we describe a molecular mechanism that allows the integration
David, Alabadí, Miguel A, Blázquez
openaire +2 more sources
IEEE Open Journal of Nanotechnology, 2021 The paper proposes novel solutions to improve the signal and thermal integrity of crossbar arrays of Resistive Random-Access Memories, that are among the most promising technologies for the 3D monolithic integration.
Khitem Lahbacha +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MicromachinesElectrical connectors play a vital role in ensuring reliable signal transmission in high-frequency microsystems. This study explores the impact of microscale scratch-induced surface roughness on the alternating current (AC) contact impedance of RF ...
Yuqi Zhou +3 more
doaj +1 more source
SI/PI-Database of PCB-Based Interconnects for Machine Learning Applications
IEEE Access, 2021 A database is presented that allows the investigation of machine learning (ML) tools and techniques in the signal integrity (SI), power integrity (PI), and electromagnetic compatibility (EMC) domains.
Morten Schierholz +7 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Revolutionize 3D-Chip Design With Open3DFlow, an Open-Source AI-Enhanced Solution
IEEE Open Journal of Circuits and SystemsThe escalating demand for high-performance and energy-efficient electronics has propelled 3D integrated circuits (3D ICs) as a promising solution. However, major obstacles have been the lack of specialized electronic design automation (EDA) software and ...
Yifei Zhu +5 more
doaj +1 more source
Engineering Reports, 2022 This article presents research conducted on the backplane high‐speed Peripheral Component Interconnect Express version 4 (PCIe gen4) link between central processor root complex and the end‐point device in order to confirm its compliance. Signal integrity
Evgeny Orekhov +2 more
doaj +1 more source