Results 51 to 60 of about 5,505,088 (293)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Power integrity enhancement in mixed-signal PDNs using diamond-based via-loaded square power island metamaterial structures

open access: yesFrontiers in Carbon
When a common power supply is shared by analog and digital circuits on a high-frequency mixed-signal board, noise generated by high-speed digital circuits propagates through the power delivery network (PDN) and degrades the performance of sensitive ...
L. K. Aishwaryaa   +3 more
doaj   +1 more source

The impact of self-heating and SiGe strain-relaxed buffer thickness on the analog performance of strained Si nMOSFETs [PDF]

open access: yes, 2010
The impact of the thickness of the silicon–germanium strain-relaxed buffer (SiGe SRB) on the analog performance of strained Si nMOSFETs is investigated.
O'Neill, Anthony G.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Metamaterial-Inspired Stub-Loaded EBG Structures for Broadband PDN Noise Mitigation in High-Speed PCBs [PDF]

open access: yesEPJ Web of Conferences
Ultra-wideband (UWB) high-speed planar circuits suffer from power/ground noise due to voltage fluctuations, ground bounce, return-path discontinuities, and plane resonances, leading to electromagnetic interference (EMI) and signal integrity (SI ...
Aishwaryaa L. K.   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

FocuS-MN: Focusing on Underwater Signal Denoising via Sequential Memory Networks with Learnable Resampling

open access: yesJournal of Marine Science and Engineering
The coupling of non-stationary marine noise and complex ship-radiated signals makes high-fidelity signal recovery exceptionally difficult. Existing deep learning methods often prioritize objective metrics, such as the Scale-Invariant Signal-to-Noise ...
Shouao Gu, Zitong Li, Jun Tang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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