Results 81 to 90 of about 337,357 (338)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Evolution of Divergent Female Mating Preference in Response to Experimental Sexual Selection [PDF]
, 2014 Sexual selection is predicted to drive the coevolution of mating signals and preferences (mating traits) within populations, and could play a role in speciation if sexual isolation arises due to mating trait divergence between populations. However, few
Debelle, A. +5 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Experimental Research of Multistatic Passive Radar With a Single Antenna for Drone Detection
IEEE Access, 2018 Digital television signals are attractive illuminations of opportunity for the passive radars in the field of low altitude and slow speed target detection.
Gao Fang +4 more
doaj +1 more source
Trends in Bioimaging and Signal Processing
This is the second in a series of three columns summarizing the "Trends" expert sessions organized by the Signal Processing Society Technical Committees during ICASSP 2011 in Prague, Czech Republic.
Laine, A. +4 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Multiband Fusion GPS Weak Signal Tracking and Acquisition Based on Opportunistic Ant Clustering [PDF]
Jisuanji gongcheng, 2018 Ant cluster network architecture of multi-space-time,high-dimensional stochastic process is built based on signal detection and tracking metadata fants dustering algorithm,so that any ant individuals according to the random access signal opportunity to ...
ZHANG Junchao,ZHAO Rongxiang,HUO Ping,FENG Jing
doaj
The Equine Endometrial Cup Reaction: A Fetomaternal Signal of Significance
Annual Review of Animal Biosciences, 2012 A remarkable feature of equine pregnancy is the development of the invasive trophoblast of the chorionic girdle and its formation of the gonadotrophin-secreting endometrial cup cells in early gestation. The details of this process have been revealed only
D. Antczak +3 more
semanticscholar +1 more source