Results 101 to 110 of about 9,988,930 (255)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

IIR array processing based fast adaptive null steering algorithm using shift-invariant subarrays

, 2012
This paper presents and investigates a fast adaptive null steering system employing infinite impulse response (IIR) array processing. The new algorithm is of considerable interest in communications where the desired signal is weak compared with the ...
Leng, S., Ser, Wee
core   +1 more source

Highlights from the Signal Processing Theory and Methods Technical Committee [In the Spotlight]

, 2020
Reports on the activities of the Signal Processing Theory and Methods Technical Committee.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care ...
Bugallo, Monica F. (author), Bermudez, Jose C.M. (author), van der Veen, A.J. (author)   +2 more
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Diagnostic significance of rhythmicity in postural hand tremor

Scientific Reports
Rhythmicity is an important feature of tremor that is widely viewed as having diagnostic significance. We hypothesized that rhythmicity might be a generic function of tremor severity, reflecting greater oscillatory entrainment of motor pathways. Postural
Patricia Weede, Günther Deuschl, Rodger J. Elble, Robin Wolke, Gerhard Schmidt, Gregor Kuhlenbäumer   +5 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Spatially regularized super-resolved constrained spherical deconvolution (SR2-CSD) of diffusion MRI data

NeuroImage
Constrained Spherical Deconvolution (CSD) is widely used to estimate the white matter fiber orientation distribution (FOD) from diffusion MRI data. Its angular resolution depends on the maximum spherical harmonic order (lmax): low lmax yields smooth but ...
Ekin Taskin, Gabriel Girard, Juan Luis Villarreal Haro, Jonathan Rafael-Patiño, Eleftherios Garyfallidis, Jean-Philippe Thiran, Erick Jorge Canales-Rodríguez   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Sharing Knowledge and Building Communities in Signal Processing

, 2006
Journal PaperThe textbook has traditionally been the fundamental tool of university teaching. The text both serves as the repository of facts and information and provides the recommended structure and sequence for teaching and learning the material ...
Jones, Douglas L., Johnson, Don, Baraniuk, Richard G., Burrus, C. Sidney   +3 more
core   +1 more source