Results 111 to 120 of about 9,637,798 (291)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
NeuroImageConstrained Spherical Deconvolution (CSD) is widely used to estimate the white matter fiber orientation distribution (FOD) from diffusion MRI data. Its angular resolution depends on the maximum spherical harmonic order (lmax): low lmax yields smooth but ...
Ekin Taskin +6 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
SIGNAL PROCESSING: ELEMENTS OF DETECTION AND ESTIMATION THEORY [PDF]
Experimental Physics of Gravitational Waves, 2000 VANNUCCI, Armando, DI BENEDETTO M. G.
openaire +3 more sources
SensorsRobotic arm-based antenna measurement systems offer the flexibility needed for advanced antenna measurement and diagnostics techniques but are typically limited by reach and sampling time.
Celia Fontá Romero +3 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Perceptual Loss Function for Neural Modelling of Audio Systems
, 2020 This work investigates alternate pre-emphasis filters used as part of the loss function during neural network training for nonlinear audio processing. In our previous work, the error-to-signal ratio loss function was used during network training, with a ...
Wright, Alec +3 more
core +1 more source
Calibration and uncertainty quantification for deep learning-based drought detection
International Journal of Applied Earth Observations and GeoinformationDroughts are hydrometeorological extreme events influenced by highly intricate land–atmosphere feedback mechanisms and climate variability. Deep learning models have recently succeeded in detecting extreme climate events and promise to uncover and ...
Mengxue Zhang +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Results in EngineeringThis work presents a dual-band Frequency Selective Surface (FSS) for improving 5G communications at millimeter-wave bands. The FSS is based on a single-layer configuration which supports dual polarization, with a unit-cell period of 4 mm x 4 mm.
Mousa Abdollahvand +4 more
doaj +1 more source