Results 61 to 70 of about 9,988,930 (255)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Signal Processing Information Base

open access: yes, 2003
Conference PaperThe SPIB (Signal Processing Information Base) project at Rice University is discussed. This information base will provide the signal processing researcher and the applications engineer with data, programs, and papers that can be accessed ...
Johnson, Don, Shami, P N
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Unbiased Injection of Signal-Dependent Noise in Variance-Stabilized Range

open access: yes, 2016
<p>The design, optimization, and validation of many image processing or image-based analysis systems often requires testing of the system performance over a dataset of images corrupted by noise at different signal-to-noise ratio regimes.
Vieira, Marcelo   +2 more
core   +1 more source

Two-Stage Convolutional Neural Network for Classification of Movement Patterns in Tremor Patients

open access: yesInformation
Accurate tremor classification is crucial for effective patient management and treatment. However, clinical diagnoses are often hindered by misdiagnoses, necessitating the development of robust technical methods.
Patricia Weede   +4 more
doaj   +1 more source

Sparse linear array with low mutual coupling ratio for DOA estimation

open access: yesIET Communications, 2021
In order to reduce the mutual coupling ratio of sparse linear array, a new linear array structure with two sparse uniform linear arrays interleaved nested, is proposed in this paper.
Fan Wu   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Digital Filters and Signal Processing [PDF]

open access: yes, 2013
Digital filters, together with signal processing, are being employed in the new technologies and information systems, and are implemented in different areas and applications.
Johansson, Håkan,, Gustafsson, Oscar,
core   +1 more source

A Cartesian encoding graph neural network for crystal structure property prediction: application to thermal ellipsoid estimation† [PDF]

open access: yesDigital Discovery
In the diffraction resolution of crystal structures, thermal ellipsoids are a critical parameter that is usually more difficult to determine than atomic positions.
Àlex Solé   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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