Results 61 to 70 of about 177,717 (302)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Automatization techniques for processing biomedical signals using machine learning methods [PDF]

open access: yes, 2008
The Signal Processing Group (Department of Signal Theory and Communications, University Carlos III, Madrid, Spain) offers the expertise of its members in the automatic processing of biomedical signals.
Artés Rodríguez, Antonio
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Hard-Decision Coded Modulation for High-Throughput Short-Reach Optical Interconnect

open access: yesEntropy, 2020
Coded modulation (CM), a combination of forward error correction (FEC) and high order modulation formats, has become a key part of modern optical communication systems.
Bin Chen   +4 more
doaj   +1 more source

Generalized linear-in-parameter models : theory and audio signal processing applications [PDF]

open access: yes, 2005
This thesis presents a mathematically oriented perspective to some basic concepts of digital signal processing. A general framework for the development of alternative signal and system representations is attained by defining a generalized linear-in ...
Paatero, Tuomas
core  

Warped wavelet bases: unitary equivalence and signal processing

open access: yes, 1993
Conference PaperThe notions of time, frequency, and scale are generalized using concepts from unitary operator theory and applied to time-frequency analysis, in particular the wavelet and short-time Fourier transform orthonormal bases and Cohen's class ...
Jones, Douglas L.   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Signal enhancement for communication systems used by fire fighters

open access: yesEURASIP Journal on Audio, Speech, and Music Processing, 2019
So-called full-face masks are essential for fire fighters to ensure respiratory protection in smoke diving incidents. While such masks are absolutely necessary for protection purposes on one hand, they impair the voice communication of fire fighters ...
Michael Brodersen   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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