Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
TCR-CD3 signal strength regulates plastic coexpression of IL-4 and IFN-γ in Tfh-like cells. [PDF]
Front ImmunolVerstegen NJM +4 more
europepmc +1 more source
Statistical analysis of atmospheric parameters, noise temperature and digital terrestrial television signal strength over Jos metropolis, Plateau state, Nigeria. [PDF]
Heliyon, 2022 Ayegba A, Ojo JS, Adediji AT.
europepmc +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells. [PDF]
ElifePark CS +9 more
europepmc +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Stability and SERS signal strength of laser-generated gold, silver, and bimetallic nanoparticles at different KCl concentrations. [PDF]
HeliyonPetrikaitė V +7 more
europepmc +1 more source
Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.
Immunity, 2021 Elliot TAE +8 more
europepmc +1 more source