Results 31 to 40 of about 6,502,084 (338)
Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.
Physiological Reviews, 2018 The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology and pathophysiology. However, many of the signaling mechanisms have been unclear.
Steven J Forrester +7 more
semanticscholar +1 more source
Disease Models & Mechanisms, 2019 The unfolded protein response (UPR) involves extensive proteome remodeling in many cellular compartments. To date, a comprehensive analysis of the UPR has not been possible because of technological limitations.
Daniel N. Itzhak +5 more
doaj +1 more source
Self-organization of signal transduction
, 2013 We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters which satisfy ...
Scheler, Gabriele
core +2 more sources
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways [PDF]
, 2008 http://dx.doi.org/10.1093/bib/bbn026Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology.
Alves +17 more
core +4 more sources
Finite-State Channel Models for Signal Transduction in Neural Systems
, 2016 Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W. +2 more
core +1 more source
Autoregulation of Nisin Biosynthesis in Lactococcus lactis by Signal Transduction [PDF]
, 1995 The post-translationally modified, antimicrobial peptide nisin is secreted by strains of Lactococcus lactis that contain the chromosomally located nisin biosynthetic gene cluster nisABTCIPRKFEG.
Buchman +43 more
core +2 more sources
Firing and signal transduction associated with an intrinsic oscillation in neuronal systems [PDF]
, 1998 We study the nonlinear firing and signal transduction of a neuron subject to both a constant stimulus and a weak periodic signal, each of which is too small to, separately, fire spikes for the neuron.
Wang, W, Wang, Y, Wang, ZD
core +1 more source
Nature Communications, 2018 How tumor cells control metastatic niche formation is not fully understood. Here, the authors show in a lung metastatic niche, high-metastatic hepatocellular carcinoma cells secrete exosomal miR-1247-3p that leads to activation of β1-integrin-NF ...
Tian Fang +15 more
doaj +1 more source
Fold-Hopf Bursting in a Model for Calcium Signal Transduction
, 2002 We study a recent model for calcium signal transduction. This model displays spiking, bursting and chaotic oscillations in accordance with experimental results. We calculate bifurcation diagrams and study the bursting behaviour in detail.
Brusch, Lutz +4 more
core +1 more source
Global, quantitative and dynamic mapping of protein subcellular localization
eLife, 2016 Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. We have developed and applied Dynamic Organellar Maps, a proteomic method that allows global mapping of protein ...
Daniel N Itzhak +3 more
doaj +1 more source