Results 31 to 40 of about 112,400 (258)

EFFECTS OF RICKSHAWS AND AUTO-RICKSHAWS ON THE CAPACITY OF URBAN SIGNALIZED INTERSECTIONS

IATSS Research, 2004
Non-motorized vehicles (i.e. rickshaws) and small size motorized vehicles (i.e. auto-rickshaws) are popular para-transit modes that provided door-to-door service in congested parts of Dhaka metropolitan area.
Md. Mizanur RAHMAN
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Safety Effectiveness of High-Speed Expressway Signals, 2005 [PDF]

, 2005
The safety benefit of signalizing intersections of high-speed divided expressways is considered. Analyses were conducted on 50 and 55 mph and on 55 mph only intersections, comparing unsignalized and signalized intersections.

core  

Agent-based optimization for multiple signalized intersections using Q-learning [PDF]

, 2014
Relieving urban traffic congestion has always been an urgent call in a dynamic traffic network. The objective of this research is to control the traffic flow within a traffic network consists of multiple signalized intersections with traffic ramp.
Chin, Yit Kwong, Yeo Kiam Beng @ Abdul Noor, Tan, Min Keng, Teo, Kenneth Tze Kin, Tze, Kenneth Kin Teo, Chuo, Helen Sin Ee   +5 more
core   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Toolbox of Countermeasures to Reduce Red Light Running Final Report, April 2012 [PDF]

, 2012
Red light running (RLR) is a problem in the US that has resulted in 165,000 injuries and 907 fatalities annually. In Iowa, RLR-related crashes make up 24.5 percent of all crashes and account for 31.7 percent of fatal and major injury crashes at ...

core  

Rear-end conflicts analysis at non-signalized intersection based on vehicles trajectory data

European Transport Research Review
With the raise of implementation of both signalized and ITS intersections at many municipalities around the world, countries such as Germany, USA, Canada and others still use the stop-control (non-signalized) intersections in their traffic network ...
Hussain A. Nasr, Helai Huang, Jieling Jin, Hanchu Zhou   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Improvement of traffic performance at intersections in Karbala city

MATEC Web of Conferences, 2018
This study deals with the evaluation of traffic performance at the road network around the old city of Karbala from the southern side, at Al-Tarbia Street and Fatima Al-Zahraa Street, through the evaluation of intersections performance.
Sofia Gandhi, Al-Haddad Abdulhaq, Al-Haydari Israa Saeed   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source