Results 41 to 50 of about 16,032 (290)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Rear-end conflicts analysis at non-signalized intersection based on vehicles trajectory data

European Transport Research Review
With the raise of implementation of both signalized and ITS intersections at many municipalities around the world, countries such as Germany, USA, Canada and others still use the stop-control (non-signalized) intersections in their traffic network ...
Hussain A. Nasr, Helai Huang, Jieling Jin, Hanchu Zhou   +3 more
doaj   +1 more source

Large Scale Evaluation of Normalized Hard-Braking Events Derived from Connected Vehicle Trajectory Data at Signalized Intersections, Roundabouts, and All-Way Stops

Future Transportation
Intersection safety has been traditionally evaluated using three to five years of crash data. Recent literature suggests that connected vehicle (CV)-derived hard braking (HB) events can provide a surrogate for crashes with only a few weeks or months of ...
Vihaan Vajpayee, Enrique D. Saldivar-Carranza, Rahul Suryakant Sakhare, Darcy M. Bullock   +3 more
doaj   +1 more source

CROSSING SPEEDS OF CARS THROUGH SIGNALIZED INTERSECTIONS

JOURNAL OF ENGINEERING SCIENCE, 2023
The article deals with the problem of traffic in three traffic-light intersections in the street network of Iasi city. Usually, the existing traffic lights do not fully take into account the size, structure and parameters of the queue of vehicles waiting at intersections; which in turn affects the traffic capacity of the intersection.
Narciza-Izabela Galusca, Silviu-Cristian Iriciuc, Gelu-Răzvan Gimiga, Diana-Nicoleta Dima, Maria-Cristina Scutaru   +4 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Accident Rates at Signalized Intersections

Transportation Research Procedia, 2017
Abstract Signalized intersections remain among the most common elements of street and road networks and types of traffic control. This is due to the fact that traffic safety at controlled intersections largely determines road safety in cities in general.
Shesterov, Eugene, Mikhailov, Alexander
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Signalized intersections and mid-blocks autonomous wireless systems based on level of service (LoS) determination IoT

Measurement: Sensors
The study tries to evaluate the effectiveness of different mid-blocks and signalized intersections using Level of Service (LOS) and v/c ratio. The present study attempts to determine the Level of Service (LOS) and v/c ratio at different mid-blocks and ...
A. Shivakrishna, K.M. Lakshmana Rao
doaj   +1 more source

Automatic Estimation of the Exposure to Lateral Collision in Signalized Intersections using Video Sensors [PDF]

, 2010
Intersections constitute one of the most dangerous elements in road systems. Traffic signals remain the most common way to control traffic at high-volume intersections and offer many opportunities to apply intelligent transportation systems to make ...
Midenet, Sophie, Saunier, Nicolas
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source