Results 41 to 50 of about 1,411 (267)

Signalized intersections and mid-blocks autonomous wireless systems based on level of service (LoS) determination IoT

Measurement: Sensors
The study tries to evaluate the effectiveness of different mid-blocks and signalized intersections using Level of Service (LOS) and v/c ratio. The present study attempts to determine the Level of Service (LOS) and v/c ratio at different mid-blocks and ...
A. Shivakrishna, K.M. Lakshmana Rao
doaj   +1 more source

Smart Cities and Data Analytics for Intelligent Transportation Systems: An Analytical Model for Scheduling Phases and Traffic Lights at Signalized Intersections

Applied Sciences, 2021
This paper is intended to improve the performance of signalized intersections, one of the most important systems of traffic control explained within the scope of smart transportation systems.
Fatih Gunes, Selim Bayrakli, Abdul Halim Zaim   +2 more
doaj   +1 more source

Evaluation of bike boxes at signalized intersections

Accident Analysis & Prevention, 2012
This paper presents a before-after study of bike boxes at 10 signalized intersections in Portland, Oregon. The bike boxes, also known as advanced stop lines or advanced stop boxes, were installed to increase visibility of cyclists and reduce conflicts between motor vehicles and cyclists, particularly in potential "right-hook" situations.
Dill, Jennifer, Monsere, Christopher M., McNeil, Nathan   +2 more
openaire   +4 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A Theoretical Model for Optimizing Signalized Intersection and Roundabout Distance Using Microsimulations

Future Transportation
Traffic congestion in urban areas is a pressing challenge, with roundabouts and signalized intersections offering different operational benefits. This study explores the integration of these two intersection types, focusing on the optimal distance ...
Mirna Klobučar, Aleksandra Deluka-Tibljaš, Sanja Šurdonja, Irena Ištoka Otković   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Optimisation of Signal-controlled Intersection Capacity

Promet - Traffic&Transportation, 2012
Road traffic safety is a complex system which combines movement of entities in precisely determined space and time dimension. Each of the entities, with their different properties, sets different requirements to road traffic system, including also other entities.
Kos, Goran, Anžek, Mario, Županović, Dino   +2 more
openaire   +4 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Pedestrian injury and human behaviour: observing road-rule violations at high-incident intersections. [PDF]

PLoS ONE, 2011
Human behaviour is an obvious, yet under-studied factor in pedestrian injury. Behavioural interventions that address rule violations by pedestrians and motorists could potentially reduce the frequency of pedestrian injury.
Jonathan Cinnamon, Nadine Schuurman, S Morad Hameed   +2 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source