Results 241 to 250 of about 1,037,302 (309)

Metabolic syndrome and kidney dysfunction: emerging molecular and cellular mechanisms at the metabolic-renal interface. [PDF]

Front Endocrinol (Lausanne)
Marshall WR, Green D, Sinha S, Kalra PA.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

EPCR in Wound Healing: Mechanisms of Action and Therapeutic Potential. [PDF]

Cells
Wang H, March L, Jackson CJ, Cross M, Xue M.   +4 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

AT1R in Central Nervous System Disorders: Unveiling Novel Mechanisms and Therapeutic Avenues for Addiction. [PDF]

Addict Biol
Lv J, Zhu D, Song S, Zhou J, Zhang X, Zhou W, Liu Y, Si Z.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Pre- and post-diagnosis signalling lipid profiles in heart failure with preserved ejection fraction: a prospective cohort study. [PDF]

EBioMedicine
Zhang L, Szili-Torok T, Lamont L, Kindt A, Harms A, Bakker SJL, Gansevoort R, de Borst MH, Hankemeier T.   +8 more
europepmc   +1 more source

The role of Notch signalling and its crosstalk with oestrogen receptor signalling in breast cancer. [PDF]

Cancer Metastasis Rev
Azadova A, Isayev O, Marco A, Brooke GN.
europepmc   +1 more source

Alveolar Lipid-Macrophage Networks at the Intersection of Pulmonary Fibrosis. [PDF]

Cells
Apte SH, Lutzky VP, Groves PL, Chambers DC.   +3 more
europepmc   +1 more source