Results 201 to 210 of about 1,988,250 (269)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Peering Through the Polymer: Tracking Small Molecules to Improve Polymer Development. [PDF]

Macromolecules
Johnson C, Shilling CM, Starck M, Brittain WDG, Mahon CS, Aguilar JA.   +5 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Interpolation and Imputation Strategies for Missing Segments in Continuous Pressure-Flow Cerebral Bio-Signals: A Systematic Scoping Review. [PDF]

Sensors (Basel)
Herath IS, Marquez I, Ryznar J, Nemoga-Stout X, Shao Y, Hasan R, Sainbhi AS, Stein KY, Vakitbilir N, Silvaggio N, Hayat M, Moon J, Bergmann T, Zeiler FA.   +13 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Late-season flow recovery and trough-aligned subsidence reveal coexisting subglacial drainage components beneath the western Greenland Ice Sheet

Andersen J, Gimbert F, Davison B, Livingstone S, Sole A, Bjørk A.   +5 more
europepmc   +1 more source

Classifying mental stress from eye tracking data: deep learning approaches for out-of-the-lab conditions. [PDF]

Sci Rep
Laut M, Dorschky E, Richer R, Rohleder N, Eskofier BM.   +4 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Visualization of the chloroplast MinE ring in living mesophyll cells of <i>Arabidopsis thaliana</i>. [PDF]

Plant Signal Behav
Fujiwara MT, Itoh RD.
europepmc   +1 more source