Results 91 to 100 of about 835,228 (309)
he prostate gland can be the site of multiple neoplastic transformation events, many of which give rise only to latent prostate cancer that does not progress to clinically detectable disease. While evidence of major subtypes of prostate cancer is lacking at the histopathological level, recent genomic analyses have provided increasing evidence for ...
STAIBANO, STEFANIA, Celetti, Angela
openaire +5 more sources
A subset of co-expressed genes in Slug-based cancer mesenchymal transition signature remains coexpressed in normal samples in a tissue-specific manner [PDF]
A recently identified gene expression signature of EMT markers containing the transcription factor Slug was found present in samples from many publicly available cancer gene expression datasets of multiple cancer types except leukemia. We also found many
Weiyi Cheng, Dimitris Anastassiou
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Automated signature generation for Zero-day polymorphic worms using a Double-honeynet [PDF]
Includes bibliographical references.This thesis proposes an accurate system for signature generation for Zero-day polymorphic worms. Thesis consists of two parts: In part one, polymorphic worm instances are collected by designing a novel Double-honeynet ...
Mohammed, Mohssen M Z E
core +1 more source
Let $E= A - iB$ be a Hermite-Biehler entire function of exponential type $τ/2$ where $A$ and $B$ are real entire, and consider $dμ(x) = dx/|E(x)|^2$. We show that the sign of the product $A B$ is an extremal signature for the space of functions of exponential type $τ$ with respect to the norm of $L^1(μ)$.
Littmann, Friedrich, Spanier, Mark
openaire +2 more sources
Graphical and Digital signature Combination for fulfilling the cultural gap
This proposal develops the concept of combining a handwritten signature, digital signature, and a smart card into an overall Public Key Infrastructure (PKI). The purpose of this proposed solution is to fulfill the cultural gap between traditional digital
Between Traditional Signature +1 more
core
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
ObjectiveTo compare survival to discharge and long-term outcomes in dogs and cats with acute-on-chronic kidney disease (ACKD) compared to acute kidney injury (AKI) treated with renal replacement therapy (RRT) and to identify factors associated with ...
Woonchan Ahn +8 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

