Results 101 to 110 of about 723,063 (319)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cryptanalysis of The Hwang-Shi Proxy Signature Scheme [PDF]

open access: yes, 2012
[[abstract]]Recently, Hwang and Shi proposed an efficient proxy signature scheme without using one-way hash functions. In their scheme, an original signer needn't send a proxy certificate to a proxy signer through secure channels.
黃明祥;Hwang, Min-Shiang
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Automated signature generation for Zero-day polymorphic worms using a Double-honeynet [PDF]

open access: yes, 2012
Includes bibliographical references.This thesis proposes an accurate system for signature generation for Zero-day polymorphic worms. Thesis consists of two parts: In part one, polymorphic worm instances are collected by designing a novel Double-honeynet ...
Mohammed, Mohssen M Z E
core  

Expression Signature

open access: yes, 2013
he prostate gland can be the site of multiple neoplastic transformation events, many of which give rise only to latent prostate cancer that does not progress to clinically detectable disease. While evidence of major subtypes of prostate cancer is lacking at the histopathological level, recent genomic analyses have provided increasing evidence for ...
STAIBANO, STEFANIA, Celetti, Angela
openaire   +5 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

On the Efficiency of Nonrepudiable Threshold Proxy Signature Scheme with Known Signers [PDF]

open access: yes, 2012
[[abstract]]In the (t,n) proxy signature scheme, the signature signed by the original signer can be signed by t or more proxy signers out of a proxy group of n proxy signers. Recently, Hsu et al.
黃明祥;Hwang, Min-Shiang
core  

Dogs and cats with acute-on-chronic kidney disease have worse outcomes than those with acute kidney injury following renal replacement therapy

open access: yesFrontiers in Veterinary Science
ObjectiveTo compare survival to discharge and long-term outcomes in dogs and cats with acute-on-chronic kidney disease (ACKD) compared to acute kidney injury (AKI) treated with renal replacement therapy (RRT) and to identify factors associated with ...
Woonchan Ahn   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Slug-based epithelial-mesenchymal transition gene signature is associated with prolonged time to recurrence in glioblastoma [PDF]

open access: yes, 2011
Background We previously identified a precise stage-associated gene expression signature of coordinately expressed genes, including the transcription factor Slug (SNAI2) and other epithelial mesenchymal transition (EMT) markers, present in ...
Jessica J. Kandel   +4 more
core   +1 more source

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