Results 121 to 130 of about 722,278 (319)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
EMERGING ISSUES FOR STATIC HANDWRITTEN SIGNATURE BIOMETRICS
, 2014 This paper presents a review of the most recent advances in static/offline signature recognition using Computer Vision and also identifies some new trends and research opportunities such as the generation of synthetic signatures, time drifting, forger ...
Ferrer, Miguel A. +5 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Modified Ohta-Okamoto Digital Signature for Batch Verification and Its Multi-Signature Version
, 2012 [[abstract]]In order to reduce the multiple-signature verification time quite, some investigations on DSA-type and RSA-type digital signatures have been done to achieve batch verification.
黃明祥;Hwang, Min-Shiang
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Cryptanalysis of Nonrepudiable Threshold Proxy Signature Schemes with Known Signers
, 2010 Sun's nonrepudiation threshold proxy signature scheme is not secure against the collusion attack. In order to guard against the attack, Hwang et al. proposed another threshold proxy signature scheme.
Hwang, Shin-jia; Chen, Chiu-chin
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Cryptanalysis of The Hwang-Shi Proxy Signature Scheme
, 2012 [[abstract]]Recently, Hwang and Shi proposed an efficient proxy signature scheme without using one-way hash functions. In their scheme, an original signer needn't send a proxy certificate to a proxy signer through secure channels.
黃明祥;Hwang, Min-Shiang
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
THE SIGNATURE AND G-SIGNATURE OF MANIFOLDS WITH BOUNDARY [PDF]
Journal of Differential Geometry, 1972 openaire +3 more sources