Results 141 to 150 of about 722,278 (319)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Cryptanalysis of Nonrepudiable Threshold Proxy Signature Schemes with Known Signers
, 2009 [[abstract]]In 2000, Hwang et al. proposed a nonrepudiable threshold proxy signature scheme to improve Sun’s scheme. In this paper, a new attack is proposed to show that, both in Hwang et al.’s and Sun’s schemes, the threshold proxy signatures can be ...
Hwang;Shin-Jia and Chen;Chiu-Chin
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Cryptanalysis of A New Multi-Proxy Multi-Signature Scheme
, 2009 [[abstract]]Recently, Hwang and Chen [5] proposed a variation of proxy signature scheme called the multi-proxy multi-signature scheme. In their scheme, an authorized group of proxy signers is allowed to sign message on behalf of a group of original ...
孫宏民;謝濱燦;林宸堂
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Emerging Role of Circular RNAs in Cardio-Oncology∗
JACC: Basic to Translational Science, 2023 Chen Gao, PhD, Yibin Wang, PhD
doaj +1 more source
THE ADVANTAGES OF WRITS AND ELECTRONIC SIGNATURE IN NATIONAL AND INTERNATIONAL TRANSACTIONS [PDF]
Ever increased use of the PC has engendered a series of issues in commercial and civil matters, in general, because many legal provisions imply the existence of writs, of copies signed and authenticated.
Florea Măgureanu, George Măgureanu
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source