Results 141 to 150 of about 723,063 (319)

A Multi-policy Threshold Signature Scheme with Traceable Participant Cosigners [PDF]

open access: yes, 2009
[[abstract]]In a (t, n) threshold scheme, the secret can be reconstructed by the cooperation of t or more users. With this basic concept, Lee devised a threshold signature scheme with multiple signing policies in 2001.
Chu, C. H.;Lin, H. F.;Chang, C. C.;Chen, C. Y.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The ring signature with adaptability [PDF]

open access: yes, 2010
[[abstract]]The concept of ring signature was first introduced by Rivest et al. in 2001. Instead of revealing the actual identity of the message signer, it specifies a set of possible signers (ring members).
Tzu-Chung Chen
core  

Concurrent Signatures [PDF]

open access: yes, 2004
Liqun Chen 0002   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A Non-repudiable Multi-Proxy Multi-Signature Scheme [PDF]

open access: yes, 2012
[[abstract]]In this paper, we shall propose a threshold multi-proxy multi-signature scheme with shared verification. In the scheme allows the group of original signers to delegate the signing capability to the designated group of proxy signers ...
黃明祥;Hwang, Min-Shiang
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Untraceable Blind Signature Schemes Based on the Discrete Logarithm Problem [PDF]

open access: yes, 2010
[[abstract]]With the help of a blind signature scheme, a requester can obtain a signature on a message from a signer such that the signer knows nothing about the content of the messages and is unable to link the resulting message-signature pair; namely ...
Cheng-Chi Lee; Min-Shiang Hwang; Wei-Pang Yang
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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