Results 161 to 170 of about 2,249,719 (290)

A Singular Signature [PDF]

Circulation, 2019
Aalap D, Narichania, Jonathan C, Makielski, Zachary D, Goldberger   +2 more
openaire   +2 more sources

Slowly progressive chest rash in an elderly woman

JAAD Case Reports, 2018
Lisa M. Tom, MD, Jules B. Lipoff, MD
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

STAG2 loss amplifies EWS-FLI1-driven microsatellite enhancer activity promoting Ewing sarcoma aggressiveness. [PDF]

Proc Natl Acad Sci U S A
Eyunni S, Chu SC, Guan ML, Louw M, Young E, Carson SE, Gong J, Cieslik M, Chinnaiyan AM, Parolia A.   +9 more
europepmc   +1 more source

Necessity is the Mother of Innovation

Forensic Science International: Synergy
Leslie Park
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Development of a Diagnostic Autoantibody Assay to a Consensus Motif for the Risk Prediction of Epstein-Barr Virus-Related Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
McCutcheon KM, Bodansky A, Ngo TT, Caspar C, Quintana S, Asaki J, Zhou J, Caillier SJ, Sharathchandra A, Waldrop G, Dandekar R, Zorn K, Tubati A, Gupta S, Sabatino JJ, Cuneo R, Oksenberg J, Wallin MT, Cree BAC, Hauser SL, Pleasure S, Derisi J, Wilson MR, and the UCSF ORIGINS/EPIC team.   +23 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

“Signature” Relapse [PDF]

Indian Journal of Psychological Medicine, 2008
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source