Results 131 to 140 of about 835,228 (309)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
THE SIGNATURE AND G-SIGNATURE OF MANIFOLDS WITH BOUNDARY [PDF]
Journal of Differential Geometry, 1972 openaire +3 more sources
A Modified Ohta-Okamoto Digital Signature for Batch Verification and Its Multi-Signature Version
, 2012 [[abstract]]In order to reduce the multiple-signature verification time quite, some investigations on DSA-type and RSA-type digital signatures have been done to achieve batch verification.
黃明祥;Hwang, Min-Shiang
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Cryptanalysis of Nonrepudiable Threshold Proxy Signature Schemes with Known Signers
, 2010 Sun's nonrepudiation threshold proxy signature scheme is not secure against the collusion attack. In order to guard against the attack, Hwang et al. proposed another threshold proxy signature scheme.
Hwang, Shin-jia; Chen, Chiu-chin
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On the Efficiency of Nonrepudiable Threshold Proxy Signature Scheme with Known Signers
, 2012 [[abstract]]In the (t,n) proxy signature scheme, the signature signed by the original signer can be signed by t or more proxy signers out of a proxy group of n proxy signers. Recently, Hsu et al.
黃明祥;Hwang, Min-Shiang
core