Results 51 to 60 of about 2,249,719 (290)

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

Cell Reports, 2015
The attenuation of protein synthesis via the phosphorylation of eIF2α is a major stress response of all eukaryotic cells. The growth-arrest- and DNA-damage-induced transcript 34 (GADD34) bound to the serine/threonine protein phosphatase 1 (PP1) is the ...
Meng S. Choy, Permeen Yusoff, Irene C. Lee, Jocelyn C. Newton, Catherine W. Goh, Rebecca Page, Shirish Shenolikar, Wolfgang Peti   +7 more
doaj   +1 more source

MicroRNA genetic signature in non-small cell lung cancer (NSCLC) Egyptian patients

The Egyptian Journal of Bronchology, 2020
Background Cancer development is associated with deregulated microRNA (miRNA) in body fluids including serum, plasma, and bronchoalveolar lavage (BAL). Early diagnosis and early treatment of lung cancer improve survival and response to treatment.
Samar A. Mansour, Amgad A. Farhat, Ayman H. Abd El-Zaher, Adel S. Bediwy, Said M. Abdou, Ayman A. Al Saka, Abdel Aziz A. Zidan   +6 more
doaj   +1 more source

Identification and verification of novel immune-related ferroptosis signature with excellent prognostic predictive and clinical guidance value in hepatocellular carcinoma

Frontiers in Genetics, 2023
Background: Immunity and ferroptosis often play a synergistic role in the progression and treatment of hepatocellular carcinoma (HCC). However, few studies have focused on identifying immune-related ferroptosis gene biomarkers.Methods: We performed ...
Wenxiu Jiang, Lili Wang, Yajuan Zhang, Hongliang Li   +3 more
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Signature-Based Gr\"obner Basis Algorithms --- Extended MMM Algorithm for computing Gr\"obner bases [PDF]

, 2013
Signature-based algorithms is a popular kind of algorithms for computing Gr\"obner bases, and many related papers have been published recently. In this paper, no new signature-based algorithms and no new proofs are presented. Instead, a view of signature-
Sun, Yao
core  

Why is Spacetime Lorentzian?

, 1993
We expand on the idea that spacetime signature should be treated as a dynamical degree of freedom in quantum field theory. It has been argued that the probability distribution for signature, induced by massless free fields, is peaked at the Lorentzian ...
A. Carlini, A. Sakharov, A. Vilenkin, G. Ellis, G. Gibbons, I. Antoniadis, I. Ya. Arefeva, J. Greensite, J. Greensite, S. Das, T. Banks, T. Dereli   +11 more
core   +2 more sources

Identification and validation of a novel HOX-related classifier signature for predicting prognosis and immune microenvironment in pediatric gliomas

Frontiers in Cell and Developmental Biology, 2023
Background: Pediatric gliomas (PGs) are highly aggressive and predominantly occur in young children. In pediatric gliomas, abnormal expression of Homeobox (HOX) family genes (HFGs) has been observed and is associated with the development and progression ...
Jiao Zhang, Xueguang Zhang, Junyan Su, Jiali Zhang, Siyao Liu, Li Han, Mengyuan Liu, Dawei Sun   +7 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Multiple Instance Hybrid Estimator for Learning Target Signatures

, 2017
Signature-based detectors for hyperspectral target detection rely on knowing the specific target signature in advance. However, target signature are often difficult or impossible to obtain.
Jiao, Changzhe, Zare, Alina
core   +1 more source

Flip signatures

Ergodic Theory and Dynamical Systems, 2022
AbstractA $D_{\infty }$ -topological Markov chain is a topological Markov chain provided with an action of the infinite dihedral group $D_{\infty }$ . It is defined by two zero-one square matrices A and J satisfying $AJ=JA^{\textsf {T}}$ and $J^2=I$ .
openaire   +3 more sources