Results 211 to 220 of about 154,876 (275)

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Magnetic Particle Imaging Distinguishes Viable and Damaged Cells by Exploiting Distinct Magnetic Signatures of Internalized Nanoparticles. [PDF]

Small Sci
Kampen L, Kosch O, Stach A, Fiebig NDC, Löwa N, Wiekhorst F, Ludwig A, Remmo A.   +7 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

BFL-SDWANTrust: Blockchain Federated-Learning-Enabled Trust Framework for Secure East-West Communication in Multi-Controller SD-WANs. [PDF]

Sensors (Basel)
Mushtaq M, Kifayat K.
europepmc   +1 more source

Pathomics Signature for Prognosis and CA19-9 Interception in Pancreatic Ductal Adenocarcinoma: A Real-Life, Multi-Center Study. [PDF]

Adv Sci (Weinh)
Chen Q, Xu Z, Zou Y, Jiang Z, Li Y, He T, Yin H, Li J, An Y, Han J, Xie Y, Gan W, Xu Y, Wang W, He J, Wang H, Wu W, Ye Z, Lou W, Hao J, Liu L, Yu J, Pu N.   +22 more
europepmc   +1 more source

The α-synuclein proteostasis network and its translational applications in Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Lim CM, Vendruscolo M.
europepmc   +1 more source

Proteotoxic stress response drives T cell exhaustion and immune evasion. [PDF]

Nature
Wang Y, Ma A, Song NJ, Shannon AE, Amankwah YS, Chen X, Wu W, Wang Z, Saadey AA, Yousif A, Ghosh G, Mandula JK, Velegraki M, Xiao T, Wen H, Huang SC, Wang R, Beusch CM, Dawood AS, Gordon DE, Abdel-Hakeem MS, Ghoneim HE, Xin G, Searle BC, Li Z.   +24 more
europepmc   +1 more source