Results 161 to 170 of about 61,318 (225)

Machine Learning‐Driven Nanopore Sensing for Quantitative, Label‐Free miRNA Detection

Small Methods, EarlyView.
Nanopore sensors combined with DNA‐barcoded probes enable detection of multiple biomarkers in parallel at the single‐molecule level through characteristic delays in ionic current signals. Three analytical strategies are compared: moving standard deviation, spectral entropy, and a convolutional neural network (CNN). The CNN achieves superior sensitivity
Caroline Koch, Seshagiri Sakthimani, Victoria Maria Noakes, Miruna Cretu, David Newman, Richard Gutierrez, Mark Bruce, Julia Gorelik, Nadia Guerra, Joshua B. Edel, Aleksandar P. Ivanov   +10 more
wiley   +1 more source

Targeting ATF6α Attenuates UVB-Induced Senescence and Improves Skin Homeostasis by Regulating IL8 Expression. [PDF]

Aging Cell
Giroud J, Delvaux P, Carlier L, De Schutter C, Martin N, Rouget R, Bolouki A, De Glas V, Bouriez I, Bourdoux F, Burteau S, Théry J, Decanter G, Penel N, de Launoit Y, Ledoux B, Abbadie C, Poumay Y, Pluquet O, Debacq-Chainiaux F.   +19 more
europepmc   +1 more source

Performance of the operational ECMWF ensemble in predicting heavy rain associated with the Emilia‐Romagna flood in May 2023

Weather, EarlyView.
A devastating flood occurred in May 2023 in the Emilia‐Romagna region in northern Italy after 2 days with widespread accumulated precipitation exceeding 150mm. The event was associated with a quasi‐stationary upper‐level cutoff cyclone. This study investigates the performance of the operational ECMWF ensemble prediction system in capturing the cutoff ...
Hei Tung Wu, Katharina Hartmuth, Heini Wernli   +2 more
wiley   +1 more source

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications. [PDF]

Nat Commun
Wang X, Venet D, Lifrange F, Larsimont D, Rediti M, Stenbeck L, Dupont F, Rouas G, Garcia AJ, Craciun L, Buisseret L, Ignatiadis M, Carausu M, Bhalla N, Masarapu Y, Villacampa EG, Franzén L, Saarenpää S, Kvastad L, Thrane K, Lundeberg J, Rothé F, Sotiriou C.   +22 more
europepmc   +1 more source

Hunting and fishing harvest data collection: a horizon scanning exercise from the French context

Wildlife Biology, EarlyView.
Legal and societal moves increasingly lead leisure hunting and fishing practitioners to record their harvest. The total number of individuals harvested per population per year is the minimum required information to feed into demographic models and allow science‐based management. Some few schemes record more detailed data, hence allowing better‐informed
Matthieu Guillemain, Léo Bacon, Aurélie Barboiron, Pierre Defos du Rau, Cyril Eraud, Aurélie Flesselle, Charlotte Francesiaz, Quentin Josset, Yoann Lechauve, Kevin Le Rest, Hervé Lormée, Maxime Passerault, Maryline Pellerin, Caroline Penil, Betty Plaquin, Adrien Tableau, Julien Terraube, Laurent Beaulaton   +17 more
wiley   +1 more source

Photochemical activation of pincer-ligated phosphoranides: mechanistic insight for reduction of aryl halides. [PDF]

Chem Sci
Escoudé E, Pedrón M, Bourqui L, Gontard G, Vitale MR, Ciofini I, Lakhdar S, Grimaud L.   +7 more
europepmc   +1 more source

Trade‐offs across life history stages and social association types shape winter communal roosting in a long‐lived raptor

Journal of Animal Ecology, EarlyView.
Our study demonstrates how life history trade‐offs and pair bonds influence winter roosting in red kites. Analysing long‐term GPS data from 216 individuals, we reveal marked behavioural plasticity in communal roosting: young, non‐breeding males are most likely to join communal roosts, whereas breeding pairs predominantly roost together near their ...
Benedetta Catitti, Lorenz P. Mindt, Adrian Aebischer, Martin U. Grüebler, Birgit C. Schlick‐Steiner, Florian M. Steiner, Urs G. Kormann   +6 more
wiley   +1 more source

p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment. [PDF]

Cell Death Dis
Yanushko D, German Falcon B, El Bizri R, Pervizou D, Dolgos R, Keime C, Ye T, Thibault-Carpentier C, Le Magnen C, Henri S, Laverny G, Metzger D.   +11 more
europepmc   +1 more source

Demographic buffering in natural populations: A multi‐level perspective

Journal of Animal Ecology, EarlyView.
We introduce a multi‐level framework that unites stochastic elasticities with nonlinear selection to test demographic buffering. Applying it across mammals reveals a key insight: ecological robustness to variability often decouples from evolutionary constraint, reshaping how we understand resilience under environmental stochasticity.
Gabriel Silva Santos, Samuel J. L. Gascoigne, André Tavares Corrêa Dias, Maja Kajin, Roberto Salguero‐Gómez   +4 more
wiley   +1 more source

Invasive <i>Acinetobacter baumannii</i> ABC141 strain relies on the twin-arginine translocation export system for adhesion to host cells. [PDF]

Microbiology (Reading)
Debruyne C, Hodge L, Hokamp K, Kröger C, Ershova AS, Salcedo SP.   +5 more
europepmc   +1 more source