Results 31 to 40 of about 179,602 (215)

Detection and evaluation of selection signatures in sheep [PDF]

Pesquisa Agropecuária Brasileira, 2018
: The recent development of genome-wide single nucleotide polymorphism (SNP) arrays made it possible to carry out several studies with different species.
Tiago do Prado Paim, Patrícia Ianella, Samuel Rezende Paiva, Alexandre Rodrigues Caetano, Concepta Margaret McManus Pimentel   +4 more
doaj   +1 more source

The study of selection signature and its applications on identification of candidate genes using whole genome sequencing data in chicken—a review

Poultry Science, 2023
: Chicken is a major source of protein for the increasing human population and is useful for research purposes. There are almost 1,600 distinct regional breeds of chicken across the globe, among which a large body of genetic and phenotypic variations has
Semiu Folaniyi Bello, Raman Akinyanju Lawal, Adeniyi Charles Adeola, Qinghua Nie   +3 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Cross-population selection signatures in Canchim composite beef cattle.

PLoS ONE, 2022
Analyses of livestock genomes have been used to detect selection signatures, which are genomic regions associated with traits under selection leading to a change in allele frequency.
Igor Nelson Herculano Duarte, Ayrton Fernandes de Oliveira Bessa, Luciana Diniz Rola, Maria Victória Henrique Genuíno, Iasmin Marques Rocha, Cintia Righetti Marcondes, Luciana Correia de Almeida Regitano, Danísio Prado Munari, Donagh Pearse Berry, Marcos Eli Buzanskas   +9 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Model selection and robust inference of mutational signatures using Negative Binomial non-negative matrix factorization

BMC Bioinformatics, 2023
Background The spectrum of mutations in a collection of cancer genomes can be described by a mixture of a few mutational signatures. The mutational signatures can be found using non-negative matrix factorization (NMF).
Marta Pelizzola, Ragnhild Laursen, Asger Hobolth   +2 more
doaj   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Genomic Analysis Reveals Pleiotropic Alleles at EDN3 and BMP7 Involved in Chicken Comb Color and Egg Production

Frontiers in Genetics, 2019
Artificial selection is often associated with numerous changes in seemingly unrelated phenotypic traits. The genetic mechanisms of correlated phenotypes probably involve pleiotropy or linkage of genes related to such phenotypes.
Xianggui Dong, Junying Li, Yuanyuan Zhang, Deping Han, Guoying Hua, Jiankui Wang, Xuemei Deng, Changxin Wu   +7 more
doaj   +1 more source

The Relationship Between Physical Activity and Left Ventricular Remodeling in Childhood Cancer Survivors Treated With Anthracyclines: A Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan, Sitong Chen, F. Lennie Wong, Nathan Young, Anna Qi, Christopher Davis, Sanjeet Hegde, Nicholas Gloude, Kasey J. Leger, Kelly D. Getz, Francisco Contijoch, Kirsten Ness, Bonnie Ky, Dennis Kuo, Sheri J. Hartman, Saro H. Armenian   +15 more
wiley   +1 more source

Genomic Survey of Selection Footprints in Three Buffalo Breeds from Eastern Europe

Animals
The buffalo is an important agricultural species due to its many productive characteristics, which encourage its use worldwide. Uncovering the processes of selective sweeps is critical for a comprehensive understanding of genomic mechanisms that ...
Medhat S. Saleh, Abdelfatah R. Zaghloul, Mayra Gómez Carpio, Claudia Pierini, Pasquale De Palo, Vincenzo Landi   +5 more
doaj   +1 more source