Results 101 to 110 of about 329,714 (296)

Edges and vertices in a unique signed circle in a signed graph

open access: yesAKCE International Journal of Graphs and Combinatorics, 2017
We examine the conditions under which a signed graph contains an edge or a vertex that is contained in a unique negative circle or a unique positive circle.
Richard Behr
doaj   +1 more source

Signed domatic number of a graph

open access: yesDiscrete Applied Mathematics, 2005
Given a graph \(G=(V, E)\), the signed dominating function is a two-valued mapping \(f : V \rightarrow \{-1, 1\}\) such that, for each vertex \(v\in V\), \(\sum_{x\in N[v]} f(x) \geq 1\), where \(N[v]=N(v)\cup\{v\}\) is the closed neighborhood of \(v\).
VolkmannLutz, ZelinkaBohdan
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Whole-Graph Representation Learning for the Classification of Signed Networks

open access: yesIEEE Access
Graphs are ubiquitous for modeling complex systems involving structured data and relationships. Consequently, graph representation learning, which aims to automatically learn low-dimensional representations of graphs, has drawn a lot of attention in ...
Noe Cecillon   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

open access: yesFEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh   +2 more
wiley   +1 more source

Computing the determinant of a signed graph

open access: yesOpen Mathematics
A signed graph is a simple graph in which every edge has a positive or negative sign. In this article, we employ several algebraic techniques to compute the determinant of a signed graph in terms of the spectrum of a vertex-deleted subgraph.
Alshamary Bader, Stanić Zoran
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

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