Results 101 to 110 of about 337,641 (297)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Computing the determinant of a signed graph

open access: yesOpen Mathematics
A signed graph is a simple graph in which every edge has a positive or negative sign. In this article, we employ several algebraic techniques to compute the determinant of a signed graph in terms of the spectrum of a vertex-deleted subgraph.
Alshamary Bader, Stanić Zoran
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

An upper bound for the Laplacian index of a signed graph [PDF]

open access: yesDiscrete Mathematics Letters, 2021
Farzaneh Ramezani, Zoran Stanic
doaj   +1 more source

GASP, a generalized framework for agglomerative clustering of signed graphs and its application to Instance Segmentation

open access: gold, 2022
Alberto Bailoni   +6 more
openalex   +2 more sources

Signed distance graphs

open access: yesJournal of Combinatorial Theory, 1969
AbstractSigned graphs are assigned to systems of points in a metric space. Special cases are investigated.
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Edge coloring of small signed graphs

open access: yesTASK Quarterly
In 2020, Behr introduced the problem of edge coloring of signed graphs and proved that every signed graph (G, sigma) can be colored using Delta(G) or Delta(G) + 1 colors, where Delta(G) denotes the maximum degree of G.
Robert Janczewski   +2 more
doaj  

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