Results 71 to 80 of about 2,708,601 (295)

The common minimal dominating signed graph [PDF]

open access: yesTransactions on Combinatorics, 2012
In this paper, we define the common minimal dominating signedgraph of a given signed graph and offer a structuralcharacterization of common minimal dominating signed graphs. Inthe sequel, we also obtained switching equivalencecharacterizations: $overline{
P. Siva Reddy, B. Prashanth
doaj  

Edge-Dual Graph Preserving Sign Prediction for Signed Social Networks

open access: yesIEEE Access, 2017
Though existing works of sign prediction have reasonable prediction performances, they suffer from the data sparseness problem, especially for the negative link prediction.
Weiwei Yuan   +3 more
doaj   +1 more source

Signed star (k,k)-domatic number of a graph [PDF]

open access: yesOpuscula Mathematica, 2014
Let \(G\) be a simple graph without isolated vertices with vertex set \(V(G)\) and edge set \(E(G)\) and let \(k\) be a positive integer. A function \(f:E(G)\longrightarrow \{-1, 1\}\) is said to be a signed star \(k\)-dominating function on \(G\) if ...
S. M. Sheikholeslami, L. Volkmann
doaj   +1 more source

Applications of Structural Balance in Signed Social Networks [PDF]

open access: yes, 2014
We present measures, models and link prediction algorithms based on the structural balance in signed social networks. Certain social networks contain, in addition to the usual 'friend' links, 'enemy' links.
Kunegis, Jérôme
core  

Strong Structural Controllability of Signed Networks

open access: yes, 2019
In this paper, we discuss the controllability of a family of linear time-invariant (LTI) networks defined on a signed graph. In this direction, we introduce the notion of positive and negative signed zero forcing sets for the controllability analysis of ...
Haeri, Mohammad   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Laplacian Spectral Properties of Signed Circular Caterpillars

open access: yesTheory and Applications of Graphs, 2020
A circular caterpillar of girth $n$ is a graph such that the removal of all pendant vertices yields a cycle $C_n$ of order $n$. A signed graph is a pair $\Gamma=(G, \sigma)$, where $G$ is a simple graph and $\sigma: E(G) \rightarrow \{+1, -1\}$ is the ...
Maurizio Brunetti
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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