Results 71 to 80 of about 5,052,226 (252)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
On eigenspaces of some compound signed graphs
In the theory of (simple) graphs the concepts of the line and subdivision graph (as compound graphs) are well-known. It is possible to consider them also in the context of (edge) signed graphs.
Sciriha, Irene +2 more
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
The common minimal dominating signed graph [PDF]
In this paper, we define the common minimal dominating signedgraph of a given signed graph and offer a structuralcharacterization of common minimal dominating signed graphs. Inthe sequel, we also obtained switching equivalencecharacterizations: $overline{
P. Siva Reddy, B. Prashanth
core
Some results on semi-total signed graphs [PDF]
A signed graph (or sigraph in short) is an ordered pair $S = (S^u,σ)$, where $S^u$ is a graph G = (V,E), called the underlying graph of S and σ:E → {+, -} is a function from the edge set E of $S^u$ into the set {+,-}, called the signature of S.
Garg, Pravin, Sinha, Deepa
core +1 more source
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
The signed directed graph for the Locke network.
The signed directed graph for the Locke network.
Yoshie Hanzawa (511239) +3 more
core +1 more source
Sign-Compatibility of Some Derived Signed Graphs [PDF]
A signed graph (or sigraph in short) is an ordered pair S = (Su, σ), where Su is a graph G = (V, E), called the underlying graph of S and σ : E → {+1, −1} is a function from the edge set E of Su into the set {+1, −1}, called the signature ...
Dhama, Ayushi, Sinha, Deepa
core +1 more source
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source

