Results 71 to 80 of about 5,052,226 (252)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

On eigenspaces of some compound signed graphs

open access: yes, 2016
In the theory of (simple) graphs the concepts of the line and subdivision graph (as compound graphs) are well-known. It is possible to consider them also in the context of (edge) signed graphs.
Sciriha, Irene   +2 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

The common minimal dominating signed graph [PDF]

open access: yes, 2012
In this paper, we define the common minimal dominating signedgraph of a given signed graph and offer a structuralcharacterization of common minimal dominating signed graphs. Inthe sequel, we also obtained switching equivalencecharacterizations: $overline{
P. Siva Reddy, B. Prashanth
core  

Some results on semi-total signed graphs [PDF]

open access: yes, 2011
A signed graph (or sigraph in short) is an ordered pair $S = (S^u,σ)$, where $S^u$ is a graph G = (V,E), called the underlying graph of S and σ:E → {+, -} is a function from the edge set E of $S^u$ into the set {+,-}, called the signature of S.
Garg, Pravin, Sinha, Deepa
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

The signed directed graph for the Locke network.

open access: yes, 2019
The signed directed graph for the Locke network.
Yoshie Hanzawa (511239)   +3 more
core   +1 more source

Sign-Compatibility of Some Derived Signed Graphs [PDF]

open access: yes, 2012
A signed graph (or sigraph in short) is an ordered pair S = (Su, σ), where Su is a graph G = (V, E), called the underlying graph of S and σ : E → {+1, −1} is a function from the edge set E of Su into the set {+1, −1}, called the signature ...
Dhama, Ayushi, Sinha, Deepa
core   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

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