Results 101 to 110 of about 8,975,030 (331)
Journal of Philosophical InvestigationsMartin Heidegger claimed that German Idealism, especially the thought of Hegel, had brought to light a deficiency in the entire rationalist tradition of philosophy, which, when exposed as clearly as Hegel had, meant that the tradition could no longer ...
Robert Pippin
doaj +1 more source
The Hitchhiker’s Guide to Testing Statistical Significance in Natural Language Processing
Annual Meeting of the Association for Computational Linguistics, 2018 Statistical significance testing is a standard statistical tool designed to ensure that experimental results are not coincidental. In this opinion/ theoretical paper we discuss the role of statistical significance testing in Natural Language Processing ...
Rotem Dror +3 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Restauration et traduction : une question de philosophie
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2011 The conservation can be viewed as a public service and also as an economical activity. How to understand such a pratice ? From a philosophical standpoint, this question is methologically challenging.
Pierre Leveau
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Ekonomika Nauki, 2016 The article presents the results of a survey completed by the executors of projects, financed within the framework of a federal target-oriented programme «Research and development in the priority areas of development of the Russian scientific ...
A. N. Petrov +2 more
doaj
Identity and Significance in the Design Team [PDF]
, 2006 The paper examines the nature of personal identity individuals in the design team are perceived to have, derived from behavioural evidence provided by other members of the team.
Smyth, H
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source