Results 191 to 200 of about 10,843,502 (349)

Zinc-Permeable Ion Channels: Effects on Intracellular Zinc Dynamics and Potential Physiological/Pathophysiological Significance

, 2015
Kōichi Inoue, Zaven O’Bryant, Zhi‐Gang Xiong   +2 more
openalex   +1 more source

SIGNIFICANCE OF THE PROTECTION OF HONEY BEES FROM BRAULOSIS (WITH A SPECIAL FOCUS ON MONTENEGRO) [PDF]

, 2019
Mirjana Bojanić Rašović
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Meaningful within-person change estimates do not identify responders to treatment. [PDF]

Alzheimers Dement
Channick JE, Hays RD.
europepmc   +1 more source

Significance of Extracellular Vesicles: Pathobiological Roles in Disease

, 2016
Seiji Yamamoto, Erika Azuma, Masashi Muramatsu, Takeru Hamashima, Yoko Ishii, Masakiyo Sasahara   +5 more
openalex   +2 more sources

Statistically significant [PDF]

Nature Medicine, 2005
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Synergistic effects of collagen membrane and mineral trioxide aggregate on odontogenic differentiation and mineralization of human dental pulp stem cells: an in vitro study. [PDF]

BMC Oral Health
Hassan N, El-Khazragy N, Ibrahim AH.
europepmc   +1 more source

Significance of the systolic murmur [PDF]

, 1967
J. P. Shillingford
openalex   +1 more source