Significant difference in Th1/Th2 paradigm induced by tuberculosis-specific antigens between IGRA-positive and IGRA-negative patients [PDF]
Frontiers in Immunology, 2022 False negative interferon-γ release assay (IGRA) results constitute the major dilemma for the diagnosis of tuberculosis (TB) infections. Herein, we conducted a cohort study to compare the host immunological response to TB-specific antigens between active
Qiang Li +8 more
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Significant difference of differential expression pyroptosis-related genes and their correlations with infiltrated immune cells in sepsis [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundSepsis is regarded as a life-threatening organ dysfunction syndrome that responds to infection. Pyroptosis, a unique form of programmed cell death, is characterized by inflammatory cytokine secretion.
Li Wang +7 more
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Significant Difference of Immune Cell Fractions and Their Correlations With Differential Expression Genes in Parkinson’s Disease [PDF]
Frontiers in Aging Neuroscience, 2021 Parkinson’s disease (PD) is the second most neurodegenerative disease in the world. T cell infiltration in the central nervous system (CNS) has provided insights that the peripheral immune cells participate in the pathogenesis of PD.
Yilin Huang +7 more
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No statistically significant difference in long term scarring outcomes of pediatric burns patients treated surgically vs. those treated conservatively [PDF]
Frontiers in Surgery, 2022 IntroductionPaediatric burns are a common clinical presentation. The long-term scar outcomes in paediatric burns patients are relatively unknown as most are discharged after 6 weeks follow up, apart from the small number that are followed up by scar ...
Riyam Mistry, Fadi Issa
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Significant Difference in Antimicrobial Resistance of Bacteria in Septic Revision between Total Knee Arthroplasty and Total Hip Arthroplasty [PDF]
Antibiotics, 2022 Antimicrobial resistance (AMR) aggravates the already difficult treatment of periprosthetic joint infections (PJI). Due to many factors influencing AMR, the correct choice of antimicrobial management remains arguable.
Stella Stevoska +6 more
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Prednisolone versus antihistamine for allergic rhinitis: No significant difference found in randomized trial [PDF]
Clinical and Translational AllergyBackground Seasonal allergic rhinitis (AR) impacts public health by affecting work productivity and quality of life. The Swedish tree pollen season starts in February with alder and hazel pollination, followed by birch and ends with oak in May.
Carl Skröder +8 more
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Significant difference in recurrence according to the proportion of high grade patterns in stage IA lung adenocarcinoma [PDF]
Thoracic Cancer, 2021 Background Patients with early lung cancer are the best candidates for surgical resection. However, those patients with high grade patterns (micropapillary or solid) do not have a good prognosis, even if they have been diagnosed with stage I lung ...
Hyun Woo Jeon +3 more
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Chloroplast genome of a pair of Triticum aestivum L. recombinant inbred lines with significant difference in seed size [PDF]
Mitochondrial DNA. Part B. Resources, 2021 Wheat (Triticum aestivum L.), one of the most important crops belong to the Triticum genus of family Poaceae. Some of important cytoplasmic genes come from chloroplast genome. In this study, the chloroplast genome of a pair of T.
Li Huaizhu, Hanjun Xue
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No significant difference in intermediate key outcomes in men with low- and intermediate-risk prostate cancer managed by active surveillance [PDF]
Scientific Reports, 2022 Active surveillance (AS) is standard of care for patients with low-risk prostate cancer (PCa), but its feasibility in intermediate-risk patients is controversial.
Karolina Cyll +6 more
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Mendelian randomization highlights significant difference and genetic heterogeneity in clinically diagnosed Alzheimer’s disease GWAS and self-report proxy phenotype GWAX [PDF]
Alzheimer’s Research & Therapy, 2022 Background Until now, Mendelian randomization (MR) studies have investigated the causal association of risk factors with Alzheimer’s disease (AD) using large-scale AD genome-wide association studies (GWAS), GWAS by proxy (GWAX), and meta-analyses of GWAS
Haijie Liu +9 more
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