Results 171 to 180 of about 276,755 (288)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Pilot Study of the Shade Matching of Biomimetic Composite Resins in Posterior Dental Restorations: Randomised Clinical Trial. [PDF]

Materials (Basel)
Rico-Romano C, Amar DA, Ducept V, Vilariño-Rodríguez RM, Garrido-Martínez P, Gutierrez-Vargas V, Mena-Álvarez J.   +6 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Overweight, Obesity, and Lifestyle Behaviors in Immigrants and Native Children in Madrid-ASOMAD Study. [PDF]

Nutrients
Nehari A, Portals-Riomao A, Quesada-González C, Zapico AG, Gesteiro E, González-Gross M.   +5 more
europepmc   +1 more source

Non-Declarative Sentences and Communication in Husserl’s Logical Investigations: contributions to a theory on communicative acts in the light of Husserl and Austin [PDF]

, 2011
Alves, Pedro M. S.
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The Use of Narratives as a Therapeutic Tool Among Latin American Immigrant Women: Processes of Reconstruction and Empowerment in Contexts of Vulnerability. [PDF]

Healthcare (Basel)
Pereñíguez MD, Palacios J, Echevarría P, Morales-Moreno I, Muñoz A.   +4 more
europepmc   +1 more source

Soins infirmiers donnés pendant la chimiothérapie aux patients atteints de tumeurs gastro-intestinales. [PDF]

Can Oncol Nurs J, 2023
Dai D, Chen J.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Construction of the Node-place-Jobs-housing model: Analysis of employment-residential ratio in subway station areas of Shenzhen, China's highest construction density zone. [PDF]

PLoS One
Liu F, Zhang J, Geng H, Zhu Y, Zhu Y, Zhou J.   +5 more
europepmc   +1 more source