Results 141 to 150 of about 87,565 (290)

Ventilatory compensation for metabolic acidosis is independent of hypertension in dogs with chronic kidney disease

Veterinary Record, EarlyView.
Abstract Introduction Metabolic acidosis is common in dogs with chronic kidney disease (CKD) and induces ventilatory compensation. Systemic arterial hypertension frequently accompanies CKD, but its influence on the ventilatory response remains unclear.
Letícia da Silva Rueda, André Leal Raymundo Pessina, Igor Luiz Salardani Senhorello, Rodrigo Prevedello Franco, Paulo Sérgio Patto dos Santos, Maria Vitoria Magalhães Dias, Lucas Ferreira Gomes, Wagner Luis Ferreira   +7 more
wiley   +1 more source

Diagnostic and Prognostic Value of Ferritin and Soluble Interleukin-2 Receptor α in Critically Ill Children with Hyperferritinemia. [PDF]

Diagnostics (Basel)
Pençe İ, Tuğrul HC, Pençe ME, Atay G, Kuraş S, Bilgün C, Erdoğan S.   +6 more
europepmc   +1 more source

Harmonizing Distributed Data in Aquatic Sciences: Key Takeaways from the 2026 ASLO‐SIL Workshop

Limnology and Oceanography Bulletin, EarlyView.
Robert T. Hensley, Bennett J. McAfee, Michael F. Meyer, Katalin Patonai, Nicolas Harrison, Kaelin M. Cawley, Frieda B. Taub, Mireia Bartrons, Asena Goren, Hans‐Peter Grossart   +9 more
wiley   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Carbon distribution in planet Mercury from magma ocean evolution to graphite crust and core composition. [PDF]

Nat Commun
Namur O, Charlier B, Cartier C, Hakim K, Villeneuve J, Tosi N, Berndt J, Klemme S, Hammouda T, Maurice M, Boyet M, Dalou C, Shorttle O.   +12 more
europepmc   +1 more source

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

Andrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel, Fabio Henrique da Silva, Jéssica Mariana Dias, Luise Gabriela Santos Pereira, Douglas Rafael Martins Dias, Amanda Bueno Olivotti, André Almeida Schenka, Valéria Barbosa de Souza, Masato Tsutsui, Fabiola Zakia Monica, Edson Antunes, Gilberto De Nucci, Mariana G. de Oliveira   +12 more
wiley   +1 more source

Initial V‐A ECMO Flow‐Index and Its Association With Inflammation, Organ Failure, and Outcomes

Artificial Organs, EarlyView.
Higher initial V‐A ECMO flow‐index was associated with greater shock severity and independently associated with multi‐organ failure. Early hemolysis may partly contribute to this association, particularly in eCPR patients, whereas no significant indirect effect through IL‐6 was observed.
Kostiantyn Kozakov, Zdenek Provaznik, Alois Philipp, Maik Foltan, Christian Schach, Sergey Vasin, Andreas Keyser, Leopold Rupprecht, Christof Schmid, Simon Schopka   +9 more
wiley   +1 more source

Network Pharmacology and Experimental Validation Elucidate the Anti-Angiogenic Mechanism of Silibinin. [PDF]

Chem Biodivers
Gu SS, Liu CQ, Yi WZ, Li YP, Xia LX, Cui YH, Huang HJ, Meng J, Pan HW.   +8 more
europepmc   +1 more source

Sil-Vara,

, 2011
s.
openaire   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source