Results 211 to 220 of about 59,140 (257)
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Journal of Pharmaceutical and Biomedical Analysis, 2019
Sildenafil is an inhibitor of the phosphodiesterase type 5 which is commonly adulterated in herbal health products. In this study, a rapid, sensitive and selective method using thin layer chromatography (TLC) combined with surface-enhanced Raman ...
D. Minh +5 more
semanticscholar +1 more source
Sildenafil is an inhibitor of the phosphodiesterase type 5 which is commonly adulterated in herbal health products. In this study, a rapid, sensitive and selective method using thin layer chromatography (TLC) combined with surface-enhanced Raman ...
D. Minh +5 more
semanticscholar +1 more source
Sildenafil treatment of vascular dementia in aged rats.
Neurochemistry International, 2019BACKGROUND and purpose: In this study, we employed a multiple microinfarction (MMI) based vascular dementia (VaD) model in aged rats and tested the therapeutic effects of Sildenafil, a phosphodiesterase type 5 inhibitor, on cognitive decline, white ...
P. Venkat +7 more
semanticscholar +1 more source
Food and Chemical Toxicology, 2018
The present study was designed to investigate the potential protective effects of diosmin (DS) and/or sildenafil against bile duct ligation (BDL). In order to achieve this goal, BDL was performed to induce liver cirrhosis, DS (100 mg/kg/day, p.o.) and ...
Fares E. M. Ali +4 more
semanticscholar +1 more source
The present study was designed to investigate the potential protective effects of diosmin (DS) and/or sildenafil against bile duct ligation (BDL). In order to achieve this goal, BDL was performed to induce liver cirrhosis, DS (100 mg/kg/day, p.o.) and ...
Fares E. M. Ali +4 more
semanticscholar +1 more source
European Journal of Pharmacology, 2018
Epilepsy is one of the furthermost common neurodegenerative diseases affecting above 50 million individuals worldwide. The pathogenesis of epileptic seizures is not satisfactorily explored, and hence more effective anti‐convulsive therapies are ...
Karima Tawfik, Y. Moustafa, M. El-Azab
semanticscholar +1 more source
Epilepsy is one of the furthermost common neurodegenerative diseases affecting above 50 million individuals worldwide. The pathogenesis of epileptic seizures is not satisfactorily explored, and hence more effective anti‐convulsive therapies are ...
Karima Tawfik, Y. Moustafa, M. El-Azab
semanticscholar +1 more source
Biochemical and Biophysical Research Communications - BBRC, 2018
To understand the molecular mechanisms underlying the beneficial effects of sildenafil in animal models of neurological disorders, we investigated the effects of sildenafil on the mitochondrial toxicity induced by β-amyloid (Aβ) peptide.
Yonghae Son, Koanhoi Kim, Hyok-rae Cho
semanticscholar +1 more source
To understand the molecular mechanisms underlying the beneficial effects of sildenafil in animal models of neurological disorders, we investigated the effects of sildenafil on the mitochondrial toxicity induced by β-amyloid (Aβ) peptide.
Yonghae Son, Koanhoi Kim, Hyok-rae Cho
semanticscholar +1 more source